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Self-adjustment of deep brain stimulation delays optimization in Parkinson's disease.
Oliveira, Lais M; Ruiz-Lopez, Marta; Boutet, Alexandre; Elias, Gavin J B; Kalia, Suneil K; Hodaie, Mojgan; Lozano, Andres M; Munhoz, Renato P; Fasano, Alfonso.
Affiliation
  • Oliveira LM; Edmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, Ontario, Canada.
  • Ruiz-Lopez M; Edmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, Ontario, Canada; Neurology Department, Cruces University Hospital, Barakaldo, Bizkaia, Spain.
  • Boutet A; Division of Neurosurgery, University Health Network, University of Toronto, Toronto, Ontario, Canada; Joint Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada.
  • Elias GJB; Division of Neurosurgery, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Kalia SK; Division of Neurosurgery, University Health Network, University of Toronto, Toronto, Ontario, Canada; Krembil Brain Institute, Toronto, Ontario, Canada; CenteR for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada.
  • Hodaie M; Division of Neurosurgery, University Health Network, University of Toronto, Toronto, Ontario, Canada; Krembil Brain Institute, Toronto, Ontario, Canada; CenteR for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada.
  • Lozano AM; Division of Neurosurgery, University Health Network, University of Toronto, Toronto, Ontario, Canada; Krembil Brain Institute, Toronto, Ontario, Canada; CenteR for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada.
  • Munhoz RP; Edmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, Ontario, Canada; Krembil Brain Institute, Toronto, Ontario, Canada.
  • Fasano A; Edmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, Ontario, Canada; Krembil Brain Institute, Toronto, Ontario, Canada; CenteR for Advancing Neurotechnological In
Brain Stimul ; 14(3): 676-681, 2021.
Article in En | MEDLINE | ID: mdl-33852934
ABSTRACT

BACKGROUND:

Parkinson's Disease patients undergo time-consuming programming to refine stimulation parameters after deep brain stimulation surgery.

OBJECTIVE:

To assess whether the use of the advanced functions of a patient's programmer would facilitate programming of deep brain stimulation.

METHODS:

Thirty patients were randomly allocated to the use of advanced versus simple mode of the patient programmer in this single-centre, prospective, randomized, controlled study. Primary outcome was the number of days required to optimize the stimulation settings.

RESULTS:

The number of days required to optimize stimulation was significantly lower in the simple mode (88.5 ± 33.1 vs. 142.1 ± 67.4, p = 0.01). In addition, the advanced mode group had a higher number of side effects (5.4 ± 3.1 vs. 2.6 ± 1.9, p = 0.0055).

CONCLUSIONS:

The use of the advanced functions of patient programmer delays programming optimization and it is associated with a higher number of side effects. These findings highlight the need for other methods for faster and safer stimulation programming.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Deep Brain Stimulation Type of study: Clinical_trials / Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: Brain Stimul Journal subject: CEREBRO Year: 2021 Document type: Article Affiliation country: Canada
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Deep Brain Stimulation Type of study: Clinical_trials / Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: Brain Stimul Journal subject: CEREBRO Year: 2021 Document type: Article Affiliation country: Canada