Self-adjustment of deep brain stimulation delays optimization in Parkinson's disease.
Brain Stimul
; 14(3): 676-681, 2021.
Article
in En
| MEDLINE
| ID: mdl-33852934
ABSTRACT
BACKGROUND:
Parkinson's Disease patients undergo time-consuming programming to refine stimulation parameters after deep brain stimulation surgery.OBJECTIVE:
To assess whether the use of the advanced functions of a patient's programmer would facilitate programming of deep brain stimulation.METHODS:
Thirty patients were randomly allocated to the use of advanced versus simple mode of the patient programmer in this single-centre, prospective, randomized, controlled study. Primary outcome was the number of days required to optimize the stimulation settings.RESULTS:
The number of days required to optimize stimulation was significantly lower in the simple mode (88.5 ± 33.1 vs. 142.1 ± 67.4, p = 0.01). In addition, the advanced mode group had a higher number of side effects (5.4 ± 3.1 vs. 2.6 ± 1.9, p = 0.0055).CONCLUSIONS:
The use of the advanced functions of patient programmer delays programming optimization and it is associated with a higher number of side effects. These findings highlight the need for other methods for faster and safer stimulation programming.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Parkinson Disease
/
Deep Brain Stimulation
Type of study:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Brain Stimul
Journal subject:
CEREBRO
Year:
2021
Document type:
Article
Affiliation country:
Canada