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5-Fluorouracil blocks quorum-sensing of biofilm-embedded methicillin-resistant Staphylococcus aureus in mice.
Sedlmayer, Ferdinand; Woischnig, Anne-Kathrin; Unterreiner, Vincent; Fuchs, Florian; Baeschlin, Daniel; Khanna, Nina; Fussenegger, Martin.
Affiliation
  • Sedlmayer F; Department of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, CH-4058 Basel, Switzerland.
  • Woischnig AK; Laboratory of Infection Biology, Department of Biomedicine, University and University Hospital Basel, Hebelstrasse 20, CH-4031 Basel, Switzerland.
  • Unterreiner V; Novartis Institutes for BioMedical Research (NIBR), Chemical Biology and Therapeutics (CBT), CH-4033, Basel, Switzerland.
  • Fuchs F; Novartis Institutes for BioMedical Research (NIBR), Chemical Biology and Therapeutics (CBT), CH-4033, Basel, Switzerland.
  • Baeschlin D; Novartis Institutes for BioMedical Research (NIBR), Chemical Biology and Therapeutics (CBT), CH-4033, Basel, Switzerland.
  • Khanna N; Laboratory of Infection Biology, Department of Biomedicine, University and University Hospital Basel, Hebelstrasse 20, CH-4031 Basel, Switzerland.
  • Fussenegger M; Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Basel, Petersgraben 4, CH-4031 Basel, Switzerland.
Nucleic Acids Res ; 49(13): e73, 2021 07 21.
Article in En | MEDLINE | ID: mdl-33856484
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biofilms / Enzyme Inhibitors / Quorum Sensing / Methicillin-Resistant Staphylococcus aureus / High-Throughput Screening Assays / Fluorouracil Limits: Animals / Female / Humans Language: En Journal: Nucleic Acids Res Year: 2021 Document type: Article Affiliation country: Switzerland Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biofilms / Enzyme Inhibitors / Quorum Sensing / Methicillin-Resistant Staphylococcus aureus / High-Throughput Screening Assays / Fluorouracil Limits: Animals / Female / Humans Language: En Journal: Nucleic Acids Res Year: 2021 Document type: Article Affiliation country: Switzerland Country of publication: United kingdom