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TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation.
Iizasa, Ei'ichi; Chuma, Yasushi; Uematsu, Takayuki; Kubota, Mio; Kawaguchi, Hiroaki; Umemura, Masayuki; Toyonaga, Kenji; Kiyohara, Hideyasu; Yano, Ikuya; Colonna, Marco; Sugita, Masahiko; Matsuzaki, Goro; Yamasaki, Sho; Yoshida, Hiroki; Hara, Hiromitsu.
Affiliation
  • Iizasa E; Department of Immunology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
  • Chuma Y; Research and Development Department, Japan BCG Laboratory, Tokyo, Japan.
  • Uematsu T; Biomedical Laboratory, Division of Biomedical Research, Kitasato University Medical Center, Kitamoto, Saitama, Japan.
  • Kubota M; Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Saga, Japan.
  • Kawaguchi H; Department of Hygiene and Health Promotion Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
  • Umemura M; Tropical Biosphere Research Center, University of the Ryukyus, Nishihara, Okinawa, Japan.
  • Toyonaga K; Department of Immunology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
  • Kiyohara H; Department of Molecular Immunology, Division of Host Defense, Research Institute for Microbial Disease, Osaka University, Osaka, Japan.
  • Yano I; Research and Development Department, Japan BCG Laboratory, Tokyo, Japan.
  • Colonna M; Research and Development Department, Japan BCG Laboratory, Tokyo, Japan.
  • Sugita M; Faculty of Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
  • Matsuzaki G; Department of Pathology and Immunology, BJC Institute of Health at Washington University, St. Louis, MO, USA.
  • Yamasaki S; Laboratory of Cell Regulation, Institute for Virus Research, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
  • Yoshida H; Tropical Biosphere Research Center, University of the Ryukyus, Nishihara, Okinawa, Japan.
  • Hara H; Department of Molecular Immunology, Division of Host Defense, Research Institute for Microbial Disease, Osaka University, Osaka, Japan.
Nat Commun ; 12(1): 2299, 2021 04 16.
Article in En | MEDLINE | ID: mdl-33863908

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / Receptors, Immunologic / Latent Tuberculosis / Immune Evasion / Mycobacterium tuberculosis / Mycolic Acids Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Japan Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / Receptors, Immunologic / Latent Tuberculosis / Immune Evasion / Mycobacterium tuberculosis / Mycolic Acids Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Japan Country of publication: United kingdom