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Inhibition of CDK4/6 kinases causes production of aneuploid oocytes by inactivating the spindle assembly checkpoint and accelerating first meiotic progression.
Dong, Feng; Meng, Tie-Gang; Li, Jian; Wang, Feng; Li, Yuan-Yuan; Ouyang, Ying-Chun; Hou, Yi; Wang, Zhen-Bo; Schatten, Heide; Sun, Qing-Yuan.
Affiliation
  • Dong F; College of Life Science, Shanxi University, Taiyuan, Shanxi 030006, PR China.
  • Meng TG; Fertility Preservation Lab, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou 510317, PR China; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, PR China.
  • Li J; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, PR China.
  • Wang F; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, PR China.
  • Li YY; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, PR China.
  • Ouyang YC; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, PR China.
  • Hou Y; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, PR China.
  • Wang ZB; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, PR China.
  • Schatten H; Department of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.
  • Sun QY; Fertility Preservation Lab, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou 510317, PR China; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, PR China. Electronic address: sunqy@gd2h.
Biochim Biophys Acta Mol Cell Res ; 1868(7): 119044, 2021 06.
Article in En | MEDLINE | ID: mdl-33865884
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclin-Dependent Kinase 4 / Cyclin-Dependent Kinase 6 / M Phase Cell Cycle Checkpoints Type of study: Etiology_studies Limits: Animals Language: En Journal: Biochim Biophys Acta Mol Cell Res Year: 2021 Document type: Article Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclin-Dependent Kinase 4 / Cyclin-Dependent Kinase 6 / M Phase Cell Cycle Checkpoints Type of study: Etiology_studies Limits: Animals Language: En Journal: Biochim Biophys Acta Mol Cell Res Year: 2021 Document type: Article Country of publication: Netherlands