A new 26-norlanostane from Phlogacanthus turgidus growing in Vietnam.
J Asian Nat Prod Res
; 24(2): 196-202, 2022 Feb.
Article
in En
| MEDLINE
| ID: mdl-33876656
Chemical investigation on chloroform extract of Phlogacanthus turgidus led to the isolation of one new compound namely turgidol, together with five known triterpenoids, lupeol, lupenone, betulin, betulinic acid, and taraxerol. Their structures and stereochemistry have been determined by 1 D and 2 D NMR analysis, high resolution mass spectrometry, and compared with those in literatures. The relative configuration of turgidol was defined using DFT-NMR chemical shift calculations and subsequent DP4+ probability method. Turgidol, betulin, and betulinic acid were evaluated for cytotoxic activity toward K562 cancer cell line and the alpha-glucosidase inhibition.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Triterpenes
/
Acanthaceae
Limits:
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
J Asian Nat Prod Res
Journal subject:
BOTANICA
/
QUIMICA
Year:
2022
Document type:
Article
Affiliation country:
Vietnam
Country of publication:
United kingdom