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The outcome of olfactory impairment in patients with otherwise paucisymptomatic coronavirus disease 2019 during the pandemic.
Jalessi, M; Bagheri, S H; Azad, Z; Firouzabadi, F D; Amini, E; Alizadeh, R; Chaibakhsh, S; Ghalehbaghi, B; Hopkins, C; Farhadi, M.
Affiliation
  • Jalessi M; Skull Base Research Centre, Tehran, Iran.
  • Bagheri SH; ENT Department and Head and Neck Research Centre, Tehran, Iran.
  • Azad Z; Skull Base Research Centre, Tehran, Iran.
  • Firouzabadi FD; ENT Department and Head and Neck Research Centre, Tehran, Iran.
  • Amini E; Skull Base Research Centre, Tehran, Iran.
  • Alizadeh R; ENT Department and Head and Neck Research Centre, Tehran, Iran.
  • Chaibakhsh S; Eye Research Centre, The Five Senses Health Institute, Hazrat Rasoul Hospital, Iran University of Medical Sciences, Tehran, Iran.
  • Ghalehbaghi B; ENT Department and Head and Neck Research Centre, Tehran, Iran.
  • Hopkins C; Guy's and St Thomas' Hospital, King's College, London, UK.
  • Farhadi M; ENT Department and Head and Neck Research Centre, Tehran, Iran.
J Laryngol Otol ; 135(5): 426-435, 2021 May.
Article in En | MEDLINE | ID: mdl-33883051
OBJECTIVE: This study aimed to measure the duration and recovery rate of olfactory loss in patients complaining of recent smell loss as their prominent symptom during the coronavirus disease 2019 outbreak. METHOD: This was a prospective telephone follow-up observational study of 243 participants who completed an online survey that started on 12 March 2020. RESULTS: After a mean of 5.5 months from the loss of smell onset, 98.3 per cent of participants reported improvement with a 71.2 per cent complete recovery rate after a median of 21 days. The chance of complete recovery significantly decreased after 131 days from the onset of loss of smell (100 per cent sensitive and 97.7 per cent specific). Younger age and isolated smell loss were associated with a rapid recovery, whereas accompanying rhinological and gastrointestinal symptoms were associated with longer loss of smell duration. CONCLUSION: Smell loss, occurring as a prominent symptom during the coronavirus disease 2019 pandemic, showed a favourable outcome. However, after 5.5 months from the onset, around 10 per cent of participants still complained of moderate or severe hyposmia.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anosmia / COVID-19 / Olfaction Disorders Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Pregnancy Country/Region as subject: Asia Language: En Journal: J Laryngol Otol Journal subject: OTORRINOLARINGOLOGIA Year: 2021 Document type: Article Affiliation country: Iran Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anosmia / COVID-19 / Olfaction Disorders Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Pregnancy Country/Region as subject: Asia Language: En Journal: J Laryngol Otol Journal subject: OTORRINOLARINGOLOGIA Year: 2021 Document type: Article Affiliation country: Iran Country of publication: United kingdom