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Exploring the dermotoxicity of the mycotoxin deoxynivalenol: combined morphologic and proteomic profiling of human epidermal cells reveals alteration of lipid biosynthesis machinery and membrane structural integrity relevant for skin barrier function.
Del Favero, Giorgia; Janker, Lukas; Neuditschko, Benjamin; Hohenbichler, Julia; Kiss, Endre; Woelflingseder, Lydia; Gerner, Christopher; Marko, Doris.
Affiliation
  • Del Favero G; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währingerstr. 38-40, 1090, Vienna, Austria. giorgia.del.favero@univie.ac.at.
  • Janker L; Core Facility Multimodal Imaging, Faculty of Chemistry, University of Vienna, Währingerstr. 38-40, 1090, Vienna, Austria. giorgia.del.favero@univie.ac.at.
  • Neuditschko B; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Währingerstr. 38-40, 1090, Vienna, Austria.
  • Hohenbichler J; Joint Metabolome Facility, Faculty of Chemistry, University of Vienna, Währingerstr. 38-40, 1090, Vienna, Austria.
  • Kiss E; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Währingerstr. 38-40, 1090, Vienna, Austria.
  • Woelflingseder L; Department of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Währingerstr. 42, 1090, Vienna, Austria.
  • Gerner C; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währingerstr. 38-40, 1090, Vienna, Austria.
  • Marko D; Core Facility Multimodal Imaging, Faculty of Chemistry, University of Vienna, Währingerstr. 38-40, 1090, Vienna, Austria.
Arch Toxicol ; 95(6): 2201-2221, 2021 06.
Article in En | MEDLINE | ID: mdl-33890134
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trichothecenes / Keratinocytes / Epidermal Cells / Lipids Limits: Humans Language: En Journal: Arch Toxicol Year: 2021 Document type: Article Affiliation country: Austria Country of publication: Germany
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trichothecenes / Keratinocytes / Epidermal Cells / Lipids Limits: Humans Language: En Journal: Arch Toxicol Year: 2021 Document type: Article Affiliation country: Austria Country of publication: Germany