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Liquid-Liquid Phase Separation Enhances TDP-43 LCD Aggregation but Delays Seeded Aggregation.
Pakravan, Donya; Michiels, Emiel; Bratek-Skicki, Anna; De Decker, Mathias; Van Lindt, Joris; Alsteens, David; Derclaye, Sylvie; Van Damme, Philip; Schymkowitz, Joost; Rousseau, Frederic; Tompa, Peter; Van Den Bosch, Ludo.
Affiliation
  • Pakravan D; Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven-University of Leuven, 3000 Leuven, Belgium.
  • Michiels E; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, 3000 Leuven, Belgium.
  • Bratek-Skicki A; Switch Laboratory, VIB-KU Leuven Center for Brain & Disease Research, 3000 Leuven, Belgium.
  • De Decker M; VIB-VUB Center for Structural Biology, 1050 Brussels, Belgium.
  • Van Lindt J; Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven-University of Leuven, 3000 Leuven, Belgium.
  • Alsteens D; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, 3000 Leuven, Belgium.
  • Derclaye S; VIB-VUB Center for Structural Biology, 1050 Brussels, Belgium.
  • Van Damme P; Institute of Life Sciences, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium.
  • Schymkowitz J; Institute of Life Sciences, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium.
  • Rousseau F; Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven-University of Leuven, 3000 Leuven, Belgium.
  • Tompa P; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, 3000 Leuven, Belgium.
  • Van Den Bosch L; Department of Neurology, University Hospitals Leuven, 3000 Leuven, Belgium.
Biomolecules ; 11(4)2021 04 08.
Article in En | MEDLINE | ID: mdl-33917983
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA-Binding Proteins / Liquid-Liquid Extraction / Protein Aggregates Limits: Humans Language: En Journal: Biomolecules Year: 2021 Document type: Article Affiliation country: Belgium
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA-Binding Proteins / Liquid-Liquid Extraction / Protein Aggregates Limits: Humans Language: En Journal: Biomolecules Year: 2021 Document type: Article Affiliation country: Belgium