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A drug-repositioning screen using splicing-sensitive fluorescent reporters identifies novel modulators of VEGF-A splicing with anti-angiogenic properties.
Star, Eleanor; Stevens, Megan; Gooding, Clare; Smith, Christopher W J; Li, Ling; Ayine, Monica Lamici; Harper, Steve J; Bates, David O; Oltean, Sebastian.
Affiliation
  • Star E; Institute of Biomedical & Clinical Sciences, Medical School, College of Medicine and Health, University of Exeter, St Luke's Campus, Exeter, EX1 2LU, UK.
  • Stevens M; Institute of Biomedical & Clinical Sciences, Medical School, College of Medicine and Health, University of Exeter, St Luke's Campus, Exeter, EX1 2LU, UK.
  • Gooding C; Department of Biochemistry, University of Cambridge, Hopkins Building, Tennis Court Road, Cambridge, CB2 1QW, UK.
  • Smith CWJ; Department of Biochemistry, University of Cambridge, Hopkins Building, Tennis Court Road, Cambridge, CB2 1QW, UK.
  • Li L; Institute of Biomedical & Clinical Sciences, Medical School, College of Medicine and Health, University of Exeter, St Luke's Campus, Exeter, EX1 2LU, UK.
  • Ayine ML; Institute of Biomedical & Clinical Sciences, Medical School, College of Medicine and Health, University of Exeter, St Luke's Campus, Exeter, EX1 2LU, UK.
  • Harper SJ; Institute of Biomedical & Clinical Sciences, Medical School, College of Medicine and Health, University of Exeter, St Luke's Campus, Exeter, EX1 2LU, UK.
  • Bates DO; Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Queen's Medical Centre, West Block, D floor, Nottingham, NG7 2UH, UK.
  • Oltean S; Institute of Biomedical & Clinical Sciences, Medical School, College of Medicine and Health, University of Exeter, St Luke's Campus, Exeter, EX1 2LU, UK. s.oltean@exeter.ac.uk.
Oncogenesis ; 10(5): 36, 2021 May 03.
Article in En | MEDLINE | ID: mdl-33941763
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Oncogenesis Year: 2021 Document type: Article Affiliation country: United kingdom Country of publication: United States
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Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Oncogenesis Year: 2021 Document type: Article Affiliation country: United kingdom Country of publication: United States