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A Randomized Phase 1 Safety, Pharmacokinetic and Pharmacodynamic Study of the Novel Myostatin Inhibitor Apitegromab (SRK-015): A Potential Treatment for Spinal Muscular Atrophy.
Barrett, Doreen; Bilic, Sanela; Chyung, Yung; Cote, Shaun M; Iarrobino, Ryan; Kacena, Katherine; Kalra, Ashish; Long, Kimberly; Nomikos, George; Place, Amy; Still, James Gordon; Vrishabhendra, Leela.
Affiliation
  • Barrett D; Scholar Rock, Inc., 301 Binney Street, 3rd Floor, Cambridge, MA, 02142, USA.
  • Bilic S; Vanadro, LLC, Urbandale, IA, USA.
  • Chyung Y; Scholar Rock, Inc., 301 Binney Street, 3rd Floor, Cambridge, MA, 02142, USA.
  • Cote SM; Scholar Rock, Inc., 301 Binney Street, 3rd Floor, Cambridge, MA, 02142, USA.
  • Iarrobino R; Scholar Rock, Inc., 301 Binney Street, 3rd Floor, Cambridge, MA, 02142, USA.
  • Kacena K; Katherine Kacena Consulting, Natick, MA, USA.
  • Kalra A; Scholar Rock, Inc., 301 Binney Street, 3rd Floor, Cambridge, MA, 02142, USA.
  • Long K; Scholar Rock, Inc., 301 Binney Street, 3rd Floor, Cambridge, MA, 02142, USA.
  • Nomikos G; Scholar Rock, Inc., 301 Binney Street, 3rd Floor, Cambridge, MA, 02142, USA. gnomikos@scholarrock.com.
  • Place A; Scholar Rock, Inc., 301 Binney Street, 3rd Floor, Cambridge, MA, 02142, USA.
  • Still JG; Clinical Development Solutions, LLC, Raleigh, NC, USA.
  • Vrishabhendra L; Medpace Clinical Pharmacology, Cincinnati, OH, USA.
Adv Ther ; 38(6): 3203-3222, 2021 06.
Article in En | MEDLINE | ID: mdl-33963971
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Muscular Atrophy, Spinal / Myostatin Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Humans Language: En Journal: Adv Ther Journal subject: TERAPEUTICA Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Muscular Atrophy, Spinal / Myostatin Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Humans Language: En Journal: Adv Ther Journal subject: TERAPEUTICA Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States