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Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.
Schmidt, Nathalie M; Wing, Peter A C; Diniz, Mariana O; Pallett, Laura J; Swadling, Leo; Harris, James M; Burton, Alice R; Jeffery-Smith, Anna; Zakeri, Nekisa; Amin, Oliver E; Kucykowicz, Stephanie; Heemskerk, Mirjam H; Davidson, Brian; Meyer, Tim; Grove, Joe; Stauss, Hans J; Pineda-Torra, Ines; Jolly, Clare; Jury, Elizabeth C; McKeating, Jane A; Maini, Mala K.
Affiliation
  • Schmidt NM; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
  • Wing PAC; Nuffield Department of Medicine, Oxford University, Oxford, UK.
  • Diniz MO; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
  • Pallett LJ; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
  • Swadling L; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
  • Harris JM; Nuffield Department of Medicine, Oxford University, Oxford, UK.
  • Burton AR; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
  • Jeffery-Smith A; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
  • Zakeri N; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
  • Amin OE; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
  • Kucykowicz S; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
  • Heemskerk MH; Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands.
  • Davidson B; Division of Surgery, University College London, London, UK.
  • Meyer T; Royal Free London NHS Foundation Trust, London, UK.
  • Grove J; Royal Free London NHS Foundation Trust, London, UK.
  • Stauss HJ; Cancer Institute, University College London, London, UK.
  • Pineda-Torra I; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
  • Jolly C; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
  • Jury EC; Division of Medicine, University College London, London, UK.
  • McKeating JA; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
  • Maini MK; Division of Medicine, University College London, London, UK.
Nat Commun ; 12(1): 2814, 2021 05 14.
Article in En | MEDLINE | ID: mdl-33990561

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Hepatitis B virus / Sterol O-Acyltransferase / Enzyme Inhibitors Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Hepatitis B virus / Sterol O-Acyltransferase / Enzyme Inhibitors Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: United kingdom