Tungsten accumulates in the intervertebral disc and vertebrae stimulating disc degeneration and upregulating markers of inflammation and pain.

Grant, M P; VanderSchee, C R; Chou, H; Bolt, A; Epure, L M; Kuter, D; Antoniou, J; Bohle, S; Mann, K K; Mwale, F

Grant, M P; VanderSchee, C R; Chou, H; Bolt, A; Epure, L M; Kuter, D; Antoniou, J; Bohle, S; Mann, K K; Mwale, F.

Affiliation

Mwale F; SMBD-Jewish General Hospital, Lady Davis Institute for Medical Research, 3755 Cote Ste-Catherine Road, Room F-602, Montreal, QC, CAN, H3T 1E2.fmwale@jgh.mcgill.ca.

Eur Cell Mater ; 41: 517-530, 2021 05 17.

Article in En | MEDLINE | ID: mdl-33999403

Subject(s)

Inflammation/metabolism; Intervertebral Disc Degeneration/chemically induced; Intervertebral Disc/drug effects; Pain/metabolism; Tungsten/adverse effects; Up-Regulation/drug effects; Animals; Biomarkers/metabolism; Cytokines/metabolism; Fibrosis/metabolism; Intervertebral Disc/metabolism; Intervertebral Disc Degeneration/metabolism; Male; Mice; Mice, Inbred C57BL

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Tungsten / Up-Regulation / Intervertebral Disc Degeneration / Inflammation / Intervertebral Disc Limits: Animals Language: En Journal: Eur Cell Mater Year: 2021 Document type: Article

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