The Intracellular Domain of CD40 is a Potent Costimulatory Element in Chimeric Antigen Receptors.

Levin-Piaeda, Ofir; Levin, Noam; Pozner, Sarah; Danieli, Adi; Weinstein-Marom, Hadas; Gross, Gideon

Levin-Piaeda, Ofir; Levin, Noam; Pozner, Sarah; Danieli, Adi; Weinstein-Marom, Hadas; Gross, Gideon.

Affiliation

Levin-Piaeda O; Immunology Laboratory, MIGAL-Galilee Research Institute, Kiryat Shmona.
Levin N; Biotechnology Department, Tel-Hai College, Upper Galilee, Israel.
Pozner S; Immunology Laboratory, MIGAL-Galilee Research Institute, Kiryat Shmona.
Danieli A; Immunology Laboratory, MIGAL-Galilee Research Institute, Kiryat Shmona.
Weinstein-Marom H; Biotechnology Department, Tel-Hai College, Upper Galilee, Israel.
Gross G; University Medical Center, Gottingen, Germany.

J Immunother ; 44(6): 209-213, 2021.

Article in En | MEDLINE | ID: mdl-34010245

Subject(s)

CD40 Antigens/immunology; Protein Interaction Domains and Motifs/immunology; Receptors, Antigen, T-Cell/immunology; Receptors, Chimeric Antigen/immunology; T-Lymphocytes/immunology; CD40 Antigens/chemistry; CD40 Antigens/metabolism; CD8-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/metabolism; Cell Line; Genetic Engineering; Humans; Immunotherapy, Adoptive/methods; Lymphocyte Activation/immunology; Plasmids/genetics; Receptors, Antigen, T-Cell/genetics; Receptors, Antigen, T-Cell/metabolism; Receptors, Chimeric Antigen/genetics; Receptors, Chimeric Antigen/metabolism; T-Lymphocytes/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Antigen, T-Cell / T-Lymphocytes / CD40 Antigens / Protein Interaction Domains and Motifs / Receptors, Chimeric Antigen Limits: Humans Language: En Journal: J Immunother Journal subject: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Year: 2021 Document type: Article Country of publication: United States

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