Possibility evaluation of the optical imaging of proton mini-beams.
Phys Med Biol
; 66(12)2021 06 07.
Article
in En
| MEDLINE
| ID: mdl-34010817
Proton therapy using mini-beams is a promising method to reduce radiation damage to normal tissue. However, distribution measurements of mini-beams are difficult due to their small structures. Since optical imaging is a possible method to measure high-resolution two-dimensional dose distribution, we conducted optical imaging of an acrylic block during the irradiation of mini-beams of protons. Mini-beams were made from a proton pencil beam irradiated to 1 mm slits made of tungsten plate. During irradiation of the mini-beams to the acrylic block, we measured the luminescence of the acrylic block using a charge-coupled device camera. With the measurements, we could obtain slit beam images that have slit shapes in the shallow area while they were uniform in their Bragg peaks, which was similar to the case of simulated optical images by Monte Carlo simulations. We confirmed that high-resolution optical imaging of mini-beams is possible and provides a promising method for efficient quality assessment of mini-beams as well as research on mini-beam therapy.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Protons
/
Proton Therapy
Type of study:
Health_economic_evaluation
Language:
En
Journal:
Phys Med Biol
Year:
2021
Document type:
Article
Affiliation country:
Japan
Country of publication:
United kingdom