A pilot study of a culturally-appropriate, educational intervention to increase participation in cancer clinical trials among African Americans and Latinos.
Cancer Causes Control
; 32(9): 953-963, 2021 Sep.
Article
in En
| MEDLINE
| ID: mdl-34046808
ABSTRACT
AIM:
Culturally-appropriate, educational programs are recommended to improve cancer clinical trial participation among African Americans and Latinos. This study investigated the effect of a culturally-appropriate, educational program on knowledge, trust in medical researchers, and intent for clinical trial participation among African Americans and Latinos in Middle Tennessee.METHOD:
Trained community health educators delivered a 30-min presentation with video testimonials to 198 participants in 13 town halls. A pre-post survey design was used to evaluate the intervention among 102 participants who completed both pre- and post-surveys one to two weeks after the session.RESULTS:
Paired-sample t-test showed significant increases in unadjusted mean scores for knowledge (p < 0.001), trust in medical researchers (p < 0.001), and willingness to participate in clinical trials (p = 0.003) after the town halls in the overall sample. After adjusting for gender and education, all three outcomes remained significant for the overall sample (knowledge p < 0.001; trust in medical researchers p < 0.001; willingness p = 0.001) and for African Americans (knowledge p < 0.001; trust in medical researchers p = 0.007; willingness p = 0.005). However, willingness to participate was no longer significant for Latinos (knowledge p < 0.001; trust in medical researchers p = 0.034; willingness p = 0.084).CONCLUSIONS:
The culturally-appropriate, educational program showed promising results for short-term, clinical trial outcomes. Further studies should examine efficacy to improve research participation outcomes.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Black or African American
/
Hispanic or Latino
/
Neoplasms
Type of study:
Clinical_trials
/
Qualitative_research
Limits:
Humans
Language:
En
Journal:
Cancer Causes Control
Journal subject:
EPIDEMIOLOGIA
/
NEOPLASIAS
Year:
2021
Document type:
Article
Affiliation country:
United States