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Synthesis and biological evaluation of a novel anticancer agent CBISC that induces DNA damage response and diminishes levels of mutant-p53.
Ronayne, Conor T; Jonnalagadda, Sravan K; Jonnalagadda, Shirisha; Nelson, Grady L; Solano, Lucas N; Palle, Hithardha; Mani, Chinnadurai; Rumbley, Jon; Holy, Jon; Mereddy, Venkatram R.
Affiliation
  • Ronayne CT; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
  • Jonnalagadda SK; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
  • Jonnalagadda S; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
  • Nelson GL; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
  • Solano LN; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA.
  • Palle H; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX, 79430, USA.
  • Mani C; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, TX, 79430, USA.
  • Rumbley J; Department of Pharmacy Practice & Pharmaceutical Sciences, University of Minnesota, Duluth, MN, 55812, USA.
  • Holy J; Department of Biomedical Sciences, University of Minnesota Medical School, Duluth, MN, 55812, USA.
  • Mereddy VR; Integrated Biosciences Graduate Program, University of Minnesota, Duluth, MN, 55812, USA; Department of Pharmacy Practice & Pharmaceutical Sciences, University of Minnesota, Duluth, MN, 55812, USA; Department of Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, MN, 55812, USA.
Biochem Biophys Res Commun ; 562: 127-132, 2021 07 12.
Article in En | MEDLINE | ID: mdl-34051576
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Tumor Suppressor Protein p53 / Mutant Proteins / Antineoplastic Agents Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2021 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Tumor Suppressor Protein p53 / Mutant Proteins / Antineoplastic Agents Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2021 Document type: Article Affiliation country: United States