DNA Damage Response in the Adaptive Arm of the Immune System: Implications for Autoimmunity.

Manolakou, Theodora; Verginis, Panayotis; Boumpas, Dimitrios T

Manolakou, Theodora; Verginis, Panayotis; Boumpas, Dimitrios T.

Affiliation

Manolakou T; Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, 115 27 Athens, Greece.
Verginis P; School of Medicine, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
Boumpas DT; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, 700 13 Heraklion, Greece.

Int J Mol Sci ; 22(11)2021 May 29.

Article in En | MEDLINE | ID: mdl-34072535

Subject(s)

Adaptive Immunity; DNA Damage; Immune System/immunology; Immune System/metabolism; Animals; Autoimmune Diseases/etiology; Autoimmune Diseases/metabolism; Autoimmune Diseases/therapy; Autoimmunity; Biomarkers; Cytokines/metabolism; DNA Repair; Dendritic Cells/immunology; Dendritic Cells/metabolism; Disease Management; Disease Susceptibility; Genomic Instability; Humans; Lymphocyte Subsets/immunology; Lymphocyte Subsets/metabolism; Signal Transduction

Key words

B cells; DNA damage response; DNA repair; T cells; adaptive immunity; autoimmunity; cytokines; immune response; lymphocytes; therapeutic opportunities

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Adaptive Immunity / Immune System Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2021 Document type: Article Affiliation country: Greece

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