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Multiplexed proteomics of autophagy-deficient murine macrophages reveals enhanced antimicrobial immunity via the oxidative stress response.
Maculins, Timurs; Verschueren, Erik; Hinkle, Trent; Choi, Meena; Chang, Patrick; Chalouni, Cecile; Rao, Shilpa; Kwon, Youngsu; Lim, Junghyun; Katakam, Anand Kumar; Kunz, Ryan C; Erickson, Brian K; Huang, Ting; Tsai, Tsung-Heng; Vitek, Olga; Reichelt, Mike; Senbabaoglu, Yasin; Mckenzie, Brent; Rohde, John R; Dikic, Ivan; Kirkpatrick, Donald S; Murthy, Aditya.
Affiliation
  • Maculins T; Department of Cancer Immunology, Genentech, South San Francisco, United States.
  • Verschueren E; Institute of Biochemistry II, Goethe University, Frankfurt am Main, Germany.
  • Hinkle T; Department of Microchemistry, Proteomics and Lipidomics, Genentech, South San Francisco, United States.
  • Choi M; Department of Microchemistry, Proteomics and Lipidomics, Genentech, South San Francisco, United States.
  • Chang P; Department of Microchemistry, Proteomics and Lipidomics, Genentech, South San Francisco, United States.
  • Chalouni C; Khoury College of Computer Sciences, Northeastern University, Boston, United States.
  • Rao S; Department of Pathology, Genentech, South San Francisco, United States.
  • Kwon Y; Department of Pathology, Genentech, South San Francisco, United States.
  • Lim J; Department of Oncology Bioinformatics, Genentech, South San Francisco, United States.
  • Katakam AK; Department of Translational Immunology, Genentech, South San Francisco, United States.
  • Kunz RC; Department of Cancer Immunology, Genentech, South San Francisco, United States.
  • Erickson BK; Department of Pathology, Genentech, South San Francisco, United States.
  • Huang T; IQ Proteomics LLC, Cambridge, United States.
  • Tsai TH; IQ Proteomics LLC, Cambridge, United States.
  • Vitek O; Khoury College of Computer Sciences, Northeastern University, Boston, United States.
  • Reichelt M; Khoury College of Computer Sciences, Northeastern University, Boston, United States.
  • Senbabaoglu Y; Department of Mathematical Sciences, Kent State University, Kent, United States.
  • Mckenzie B; Khoury College of Computer Sciences, Northeastern University, Boston, United States.
  • Rohde JR; Department of Pathology, Genentech, South San Francisco, United States.
  • Dikic I; Department of Oncology Bioinformatics, Genentech, South San Francisco, United States.
  • Kirkpatrick DS; Department of Translational Immunology, Genentech, South San Francisco, United States.
  • Murthy A; Department of Microbiology and Immunology, Dalhousie University, Halifax, Canada.
Elife ; 102021 06 04.
Article in En | MEDLINE | ID: mdl-34085925

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Shigella flexneri / Autophagy / Oxidative Stress / Proteome / Proteomics / Dysentery, Bacillary / Autophagy-Related Proteins / Immunity, Innate / Macrophages Type of study: Prognostic_studies Limits: Animals Language: En Journal: Elife Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Shigella flexneri / Autophagy / Oxidative Stress / Proteome / Proteomics / Dysentery, Bacillary / Autophagy-Related Proteins / Immunity, Innate / Macrophages Type of study: Prognostic_studies Limits: Animals Language: En Journal: Elife Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom