An Autopsy Case of Multicentric Castleman Disease Presenting with Severe Jaundice.
Intern Med
; 60(22): 3615-3620, 2021 Nov 15.
Article
in En
| MEDLINE
| ID: mdl-34092729
ABSTRACT
A 70-year-old man with multicentric Castleman disease (MCD) was admitted to our hospital with jaundice and ascites. Elevations in his bilirubin and interleukin-6 levels were noted, and computed tomography revealed hepatic atrophy and portal vein and bile duct disorders. Steroid therapy was started for MCD, but he died of hepatic failure. An autopsy revealed that the MCD activity was mild, but advanced fibrosis and cholestasis were observed in the liver. Mild infiltration of interleukin-6-positive plasma cells was noted in the highly fibrotic area of the liver. Although rare, liver and biliary tract damage may be also considered organ disorders of MCD.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Castleman Disease
/
Liver Failure
/
Jaundice
Type of study:
Diagnostic_studies
/
Etiology_studies
Limits:
Aged
/
Humans
/
Male
Language:
En
Journal:
Intern Med
Journal subject:
MEDICINA INTERNA
Year:
2021
Document type:
Article
Affiliation country:
Japan