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Advanced maternal age causes premature placental senescence and malformation via dysregulated α-Klotho expression in trophoblasts.
Chen, Zhi; Xiong, Liling; Jin, Huili; Yu, Jiaxiao; Li, Xin; Fu, Huijia; Wen, Li; Qi, Hongbo; Tong, Chao; Saffery, Richard; Kilby, Mark D; Baker, Philip N.
Affiliation
  • Chen Z; Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Xiong L; State Key Laboratory of Maternal and Fetal Medicine of Chongqing Municipality, Chongqing Medical University, Chongqing, China.
  • Jin H; International Collaborative Laboratory of Reproduction and Development of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Yu J; Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Li X; State Key Laboratory of Maternal and Fetal Medicine of Chongqing Municipality, Chongqing Medical University, Chongqing, China.
  • Fu H; International Collaborative Laboratory of Reproduction and Development of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Wen L; Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Qi H; State Key Laboratory of Maternal and Fetal Medicine of Chongqing Municipality, Chongqing Medical University, Chongqing, China.
  • Tong C; International Collaborative Laboratory of Reproduction and Development of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Saffery R; Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Kilby MD; State Key Laboratory of Maternal and Fetal Medicine of Chongqing Municipality, Chongqing Medical University, Chongqing, China.
  • Baker PN; International Collaborative Laboratory of Reproduction and Development of Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.
Aging Cell ; 20(7): e13417, 2021 07.
Article in En | MEDLINE | ID: mdl-34105233
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Placenta / Trophoblasts / Klotho Proteins Type of study: Etiology_studies Limits: Animals / Female / Humans / Pregnancy Language: En Journal: Aging Cell Year: 2021 Document type: Article Affiliation country: China Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Placenta / Trophoblasts / Klotho Proteins Type of study: Etiology_studies Limits: Animals / Female / Humans / Pregnancy Language: En Journal: Aging Cell Year: 2021 Document type: Article Affiliation country: China Country of publication: United kingdom