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Panobinostat penetrates the blood-brain barrier and achieves effective brain concentrations in a murine model.
Homan, Morgan J; Franson, Andrea; Ravi, Karthik; Roberts, Holly; Pai, Manjunath P; Liu, Cai; He, Miao; Matvekas, Aleksas; Koschmann, Carl; Marini, Bernard L.
Affiliation
  • Homan MJ; Department of Clinical Pharmacy and Pharmacy Services, University of Michigan College of Pharmacy, 1540 E. Hospital Dr., CW 7-251B, Ann Arbor, MI, 48109-5008, US.
  • Franson A; University of Michigan Medical School, Ann Arbor, MI, US.
  • Ravi K; University of Michigan Medical School, Ann Arbor, MI, US.
  • Roberts H; University of Michigan Medical School, Ann Arbor, MI, US.
  • Pai MP; University of Michigan College of Pharmacy, Ann Arbor, MI, US.
  • Liu C; University of Michigan College of Pharmacy, Ann Arbor, MI, US.
  • Matvekas A; University of Michigan College of Pharmacy, Ann Arbor, MI, US.
  • Koschmann C; University of Michigan Medical School, Ann Arbor, MI, US.
  • Marini BL; Department of Clinical Pharmacy and Pharmacy Services, Inpatient Hematology, University of Michigan College of Pharmacy, 1540 E. Hospital Dr., CW 7-251B, Ann Arbor, MI, 48109-5008, US. bernmari@med.umich.edu.
Cancer Chemother Pharmacol ; 88(3): 555-562, 2021 09.
Article in En | MEDLINE | ID: mdl-34115161
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Blood-Brain Barrier / Histone Deacetylase Inhibitors / Panobinostat Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cancer Chemother Pharmacol Year: 2021 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Blood-Brain Barrier / Histone Deacetylase Inhibitors / Panobinostat Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cancer Chemother Pharmacol Year: 2021 Document type: Article Affiliation country: United States