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Synthesis of Tribenzo[b,d,f]azepines via Palladium-Catalyzed Annulation Reaction of 2-Iodobiphenyls with 2-Halogenoanilines.
Fang, Mao-Ying; Chen, Li-Ping; Huang, Lin; Fang, Dong-Mei; Chen, Xiao-Zhen; Wang, Bi-Qin; Feng, Chun; Xiang, Shi-Kai.
Affiliation
  • Fang MY; College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, P. R. China.
  • Chen LP; College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, P. R. China.
  • Huang L; College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, P. R. China.
  • Fang DM; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, P. R. China.
  • Chen XZ; Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, P. R. China.
  • Wang BQ; College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, P. R. China.
  • Feng C; College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, P. R. China.
  • Xiang SK; College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, P. R. China.
J Org Chem ; 86(13): 9096-9106, 2021 Jul 02.
Article in En | MEDLINE | ID: mdl-34128663
A palladium-catalyzed annulation reaction of 2-iodobiphenyls with 2-halogenoanilines has been developed. A variety of 2-iodobiphenyls and 2-halogenoanilines can undergo this transformation. Diversified tribenzo[b,d,f]azepine derivatives can be synthesized in moderate to excellent yields according to this method.

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Org Chem Year: 2021 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Org Chem Year: 2021 Document type: Article Country of publication: United States