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Site-specific Incorporation of 2',5'-Linked Nucleic Acids Enhances Therapeutic Profile of Antisense Oligonucleotides.
Prakash, Thazha P; Yu, Jinghua; Shen, Wen; De Hoyos, Cheryl Li; Berdeja, Andres; Gaus, Hans; Liang, Xue-Hai; Crooke, Stanley T; Seth, Punit P.
Affiliation
  • Prakash TP; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Yu J; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Shen W; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • De Hoyos CL; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Berdeja A; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Gaus H; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Liang XH; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Crooke ST; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, California 92010, United States.
  • Seth PP; Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, California 92010, United States.
ACS Med Chem Lett ; 12(6): 922-927, 2021 Jun 10.
Article in En | MEDLINE | ID: mdl-34141070
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States