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Role of toll-like receptor 7/8 pathways in regulation of interferon response and inflammatory mediators during SARS-CoV2 infection and potential therapeutic options.
Dyavar, Shetty Ravi; Singh, Rahul; Emani, Rohini; Pawar, Ganesh P; Chaudhari, Vinod D; Podany, Anthony T; Avedissian, Sean N; Fletcher, Courtney V; Salunke, Deepak B.
Affiliation
  • Dyavar SR; University of Nebraska Medical Center (UNMC) Center for Drug Discovery, UNMC, Omaha, NE 68198, USA. Electronic address: rdyavar@adicetbio.com.
  • Singh R; Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University, Chandigarh 160014, India.
  • Emani R; Buck Institute for Research on Ageing, Novato, CA, USA.
  • Pawar GP; Division of Medicinal Chemistry, CSIR-Institute of Microbiology Technology Chandigarh, Sector-39A, Chandigarh,160036, India.
  • Chaudhari VD; Division of Medicinal Chemistry, CSIR-Institute of Microbiology Technology Chandigarh, Sector-39A, Chandigarh,160036, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
  • Podany AT; University of Nebraska Medical Center (UNMC) Center for Drug Discovery, UNMC, Omaha, NE 68198, USA.
  • Avedissian SN; University of Nebraska Medical Center (UNMC) Center for Drug Discovery, UNMC, Omaha, NE 68198, USA.
  • Fletcher CV; University of Nebraska Medical Center (UNMC) Center for Drug Discovery, UNMC, Omaha, NE 68198, USA.
  • Salunke DB; Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University, Chandigarh 160014, India; National Interdisciplinary Centre of Vaccine, Immunotherapeutics and Antimicrobials, Panjab University, Chandigarh, 160014, India. Electronic address: salunke@pu.ac.in.
Biomed Pharmacother ; 141: 111794, 2021 Sep.
Article in En | MEDLINE | ID: mdl-34153851
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Interferons / Inflammation Mediators / Toll-Like Receptor 7 / Toll-Like Receptor 8 / COVID-19 Limits: Humans Language: En Journal: Biomed Pharmacother Year: 2021 Document type: Article Country of publication: France
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Interferons / Inflammation Mediators / Toll-Like Receptor 7 / Toll-Like Receptor 8 / COVID-19 Limits: Humans Language: En Journal: Biomed Pharmacother Year: 2021 Document type: Article Country of publication: France