Determination of acyclovir and its metabolite 9-carboxymethoxymethylguanide in human serum by ultra-high-performance liquid chromatography-tandem mass spectrometry.

Urinovska, Romana; Kacirova, Ivana; Sagan, Jiri

Urinovska, Romana; Kacirova, Ivana; Sagan, Jiri.

Affiliation

Urinovska R; Departments of Clinical Pharmacology and Laboratory Medicine, University Hospital Ostrava, Ostrava, Czech Republic.
Kacirova I; Department of Clinical Pharmacology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic.
Sagan J; Departments of Clinical Pharmacology and Laboratory Medicine, University Hospital Ostrava, Ostrava, Czech Republic.

J Sep Sci ; 44(16): 3080-3088, 2021 Aug.

Article in En | MEDLINE | ID: mdl-34165890

Subject(s)

Acyclovir/analysis; Chromatography, High Pressure Liquid/methods; Guanine/analogs & derivatives; Tandem Mass Spectrometry/methods; Acetonitriles/chemistry; Adolescent; Adult; Aged; Aged, 80 and over; Calibration; Chemistry Techniques, Analytical/standards; Female; Formates/chemistry; Guanine/analysis; Humans; Limit of Detection; Male; Mass Spectrometry; Middle Aged; Quality Control; Reproducibility of Results; Young Adult

Key words

9-carboxymethoxymethylguanine; acyclovir; mass spectrometry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acyclovir / Chromatography, High Pressure Liquid / Tandem Mass Spectrometry / Guanine Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Sep Sci Year: 2021 Document type: Article Affiliation country: Czech Republic Country of publication: Germany

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