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SENTI-101, a Preparation of Mesenchymal Stromal Cells Engineered to Express IL12 and IL21, Induces Localized and Durable Antitumor Immunity in Preclinical Models of Peritoneal Solid Tumors.
Gonzalez-Junca, Alba; Liu, Frances D; Nagaraja, Archana S; Mullenix, Alyssa; Lee, Chen-Ting; Gordley, Russell M; Frimannsson, Daniel O; Maller, Ori; Garrison, Brian S; Iyer, Dharini; Benabbas, Anissa; Truong, Tiffany A; Quach, Allison; Tian, Mengxi; Martinez, Rowena; Savur, Rishi; Perry-McNamara, Alyssa; Nguyen, Denny; Almudhfar, Niran; Blanco, Carmina; Huynh, Christina; Nand, Asish; Lay, Yu-An E; Magal, Ashita; Mangalampalli, Sravani; Lee, Philip J; Lu, Timothy K; Lee, Gary.
Affiliation
  • Gonzalez-Junca A; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California. alba.gonzalez@sentibio.com.
  • Liu FD; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Nagaraja AS; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Mullenix A; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Lee CT; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Gordley RM; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Frimannsson DO; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Maller O; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Garrison BS; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Iyer D; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Benabbas A; Department of Technology and Operations, Senti Biosciences, Inc., South San Francisco, California.
  • Truong TA; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Quach A; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Tian M; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Martinez R; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Savur R; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Perry-McNamara A; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Nguyen D; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Almudhfar N; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Blanco C; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
  • Huynh C; Department of Technology and Operations, Senti Biosciences, Inc., South San Francisco, California.
  • Nand A; Department of Technology and Operations, Senti Biosciences, Inc., South San Francisco, California.
  • Lay YE; Department of Technology and Operations, Senti Biosciences, Inc., South San Francisco, California.
  • Magal A; Department of Technology and Operations, Senti Biosciences, Inc., South San Francisco, California.
  • Mangalampalli S; Department of Technology and Operations, Senti Biosciences, Inc., South San Francisco, California.
  • Lee PJ; Department of Technology and Operations, Senti Biosciences, Inc., South San Francisco, California.
  • Lu TK; Department of Technology and Operations, Senti Biosciences, Inc., South San Francisco, California.
  • Lee G; Department of Research and Development, Senti Biosciences, Inc., South San Francisco, California.
Mol Cancer Ther ; 20(9): 1508-1520, 2021 09.
Article in En | MEDLINE | ID: mdl-34210826

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peritoneal Neoplasms / Melanoma, Experimental / Interleukins / Interleukin-12 / Mesenchymal Stem Cell Transplantation / Mesenchymal Stem Cells / Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2021 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peritoneal Neoplasms / Melanoma, Experimental / Interleukins / Interleukin-12 / Mesenchymal Stem Cell Transplantation / Mesenchymal Stem Cells / Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2021 Document type: Article