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Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer.
Luu, Maik; Riester, Zeno; Baldrich, Adrian; Reichardt, Nicole; Yuille, Samantha; Busetti, Alessandro; Klein, Matthias; Wempe, Anne; Leister, Hanna; Raifer, Hartmann; Picard, Felix; Muhammad, Khalid; Ohl, Kim; Romero, Rossana; Fischer, Florence; Bauer, Christian A; Huber, Magdalena; Gress, Thomas M; Lauth, Matthias; Danhof, Sophia; Bopp, Tobias; Nerreter, Thomas; Mulder, Imke E; Steinhoff, Ulrich; Hudecek, Michael; Visekruna, Alexander.
Affiliation
  • Luu M; Institute for Medical Microbiology and Hygiene, Philipps-University Marburg, Marburg, Germany.
  • Riester Z; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.
  • Baldrich A; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.
  • Reichardt N; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.
  • Yuille S; 4DPharma Research Ltd., Aberdeen, United Kingdom.
  • Busetti A; 4DPharma Research Ltd., Aberdeen, United Kingdom.
  • Klein M; 4DPharma Research Ltd., Aberdeen, United Kingdom.
  • Wempe A; Institute for Immunology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.
  • Leister H; Institute for Medical Microbiology and Hygiene, Philipps-University Marburg, Marburg, Germany.
  • Raifer H; Institute for Medical Microbiology and Hygiene, Philipps-University Marburg, Marburg, Germany.
  • Picard F; Flow Cytometry Core Facility, Philipps University Marburg, Marburg, Germany.
  • Muhammad K; Institute for Medical Microbiology and Hygiene, Philipps-University Marburg, Marburg, Germany.
  • Ohl K; Department of Biology, United Arab Emirates University, Al Ain, United Arab Emirates.
  • Romero R; Department of Pediatrics, RWTH Aachen University, Aachen, Germany.
  • Fischer F; Institute for Medical Microbiology and Hygiene, Philipps-University Marburg, Marburg, Germany.
  • Bauer CA; Institute for Medical Microbiology and Hygiene, Philipps-University Marburg, Marburg, Germany.
  • Huber M; Department of Gastroenterology, Endocrinology, Metabolism and Infectiology, University Hospital Marburg, UKGM, Philipps University Marburg, Marburg, Germany.
  • Gress TM; Institute for Medical Microbiology and Hygiene, Philipps-University Marburg, Marburg, Germany.
  • Lauth M; Department of Gastroenterology, Endocrinology, Metabolism and Infectiology, University Hospital Marburg, UKGM, Philipps University Marburg, Marburg, Germany.
  • Danhof S; Institute of Molecular Biology and Tumor Research, Center for Tumor- and Immunobiology, Philipps-University Marburg, Marburg, Germany.
  • Bopp T; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.
  • Nerreter T; Institute for Immunology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.
  • Mulder IE; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.
  • Steinhoff U; 4DPharma Research Ltd., Aberdeen, United Kingdom.
  • Hudecek M; Institute for Medical Microbiology and Hygiene, Philipps-University Marburg, Marburg, Germany.
  • Visekruna A; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany. Hudecek_M@ukw.de.
Nat Commun ; 12(1): 4077, 2021 07 01.
Article in En | MEDLINE | ID: mdl-34210970
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Cytotoxic / Immunotherapy, Adoptive / CD8-Positive T-Lymphocytes / Fatty Acids, Volatile / Microbiota / Immunologic Factors / Neoplasms Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Germany Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Cytotoxic / Immunotherapy, Adoptive / CD8-Positive T-Lymphocytes / Fatty Acids, Volatile / Microbiota / Immunologic Factors / Neoplasms Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Germany Country of publication: United kingdom