Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis.
Mucosal Immunol
; 14(5): 1172-1182, 2021 09.
Article
in En
| MEDLINE
| ID: mdl-34226674
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Signal Transduction
/
Interleukin-2
/
Colitis
/
Genetic Predisposition to Disease
/
Gene Duplication
/
Interleukin-2 Receptor alpha Subunit
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Mucosal Immunol
Journal subject:
ALERGIA E IMUNOLOGIA
Year:
2021
Document type:
Article
Affiliation country:
Netherlands
Country of publication:
United States