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A physiologically based pharmacokinetic/pharmacodynamic modeling approach for drug-drug interaction evaluation of warfarin enantiomers with sorafenib.
Wang, Ziteng; Xiang, Xiaoqiang; Liu, Shuaibing; Tang, Zhijia; Sun, Hong; Parvez, Masud; Ghim, Jong-Lyul; Shin, Jae-Gook; Cai, Weimin.
Affiliation
  • Wang Z; Department of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, 201203, China.
  • Xiang X; Department of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, 201203, China.
  • Liu S; Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
  • Tang Z; Department of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, 201203, China.
  • Sun H; Department of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, 201203, China.
  • Parvez M; Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Busan, 614735, Republic of Korea.
  • Ghim JL; Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Busan, 614735, Republic of Korea.
  • Shin JG; Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Busan, 614735, Republic of Korea. Electronic address: phshinjg@gmail.com.
  • Cai W; Department of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, 201203, China. Electronic address: weimincai@fudan.edu.cn.
Drug Metab Pharmacokinet ; 39: 100362, 2021 Aug.
Article in En | MEDLINE | ID: mdl-34242938
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Warfarin / Blood Coagulation / Drug Interactions / Vitamin K Epoxide Reductases / Cytochrome P-450 CYP2C9 / Sorafenib / Hemorrhage Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Drug Metab Pharmacokinet Journal subject: FARMACOLOGIA / METABOLISMO Year: 2021 Document type: Article Affiliation country: China Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Warfarin / Blood Coagulation / Drug Interactions / Vitamin K Epoxide Reductases / Cytochrome P-450 CYP2C9 / Sorafenib / Hemorrhage Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Drug Metab Pharmacokinet Journal subject: FARMACOLOGIA / METABOLISMO Year: 2021 Document type: Article Affiliation country: China Country of publication: United kingdom