An uncommon [K+(Mg2+)2] metal ion triad imparts stability and selectivity to the Guanidine-I riboswitch.

Trachman, Robert J; Ferré-D'Amaré, Adrian R

An uncommon [K⁺(Mg²⁺)₂] metal ion triad imparts stability and selectivity to the Guanidine-I riboswitch.

Trachman, Robert J; Ferré-D'Amaré, Adrian R.

Affiliation

Trachman RJ; Biochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20892-8012, USA.
Ferré-D'Amaré AR; Biochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20892-8012, USA.

RNA ; 27(10): 1257-1264, 2021 10.

Article in En | MEDLINE | ID: mdl-34257148

Subject(s)

Burkholderia/genetics; Chelating Agents/chemistry; Guanidines/chemistry; Magnesium/chemistry; Potassium/chemistry; Riboswitch; Aptamers, Nucleotide/chemistry; Aptamers, Nucleotide/genetics; Aptamers, Nucleotide/metabolism; Base Pairing; Base Sequence; Biological Evolution; Burkholderia/metabolism; Chelating Agents/metabolism; Clostridiales/genetics; Clostridiales/metabolism; Crystallography, X-Ray; Dickeya/genetics; Dickeya/metabolism; Guanidines/metabolism; Magnesium/metabolism; Models, Molecular; Mutation; Nucleic Acid Conformation; Potassium/metabolism; Ribosomes/genetics; Ribosomes/metabolism; Water/chemistry; Water/metabolism

Key words

evolution; guanidine; potassium; riboswitch; structure

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Potassium / Chelating Agents / Burkholderia / Riboswitch / Guanidines / Magnesium Language: En Journal: RNA Journal subject: BIOLOGIA MOLECULAR Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States

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