Nicotine affects tight junction barriers via alpha7 nicotine-like acetylcholine receptor in keratinocytes.

Nagata, Haruna; Takagi, Nao; Inoue, Shintaro; Mizutani, Yukiko

Nagata, Haruna; Takagi, Nao; Inoue, Shintaro; Mizutani, Yukiko.

Affiliation

Nagata H; Department of Cosmetic Health Science, Gifu Pharmaceutical University, Gifu, Japan.
Takagi N; Department of Cosmetic Health Science, Gifu Pharmaceutical University, Gifu, Japan.
Inoue S; Department of Cosmetic Health Science, Gifu Pharmaceutical University, Gifu, Japan. Electronic address: inoshin@gifu-pu.ac.jp.
Mizutani Y; Department of Cosmetic Health Science, Gifu Pharmaceutical University, Gifu, Japan. Electronic address: mizutani@gifu-pu.ac.jp.

J Dermatol Sci ; 103(3): 183-185, 2021 Sep.

Article in En | MEDLINE | ID: mdl-34266725

Subject(s)

Keratinocytes/pathology; Nicotine/adverse effects; Smoking/adverse effects; Tight Junctions/pathology; alpha7 Nicotinic Acetylcholine Receptor/metabolism; Benzamides/pharmacology; Bridged Bicyclo Compounds/pharmacology; Cell Culture Techniques, Three Dimensional; Cell Line; Cell Survival; Down-Regulation/drug effects; Humans; Keratinocytes/cytology; Signal Transduction/drug effects; Tight Junctions/drug effects; Tight Junctions/metabolism; Zonula Occludens-1 Protein/analysis; Zonula Occludens-1 Protein/metabolism; alpha7 Nicotinic Acetylcholine Receptor/agonists

Key words

Nicotine; Psoriasis; Smoking; Tight junction; Zonula occludens-1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Smoking / Keratinocytes / Tight Junctions / Alpha7 Nicotinic Acetylcholine Receptor / Nicotine Limits: Humans Language: En Journal: J Dermatol Sci Journal subject: DERMATOLOGIA Year: 2021 Document type: Article Affiliation country: Japan Country of publication: Netherlands

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