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The role of sFlt1/PlGF ratio in the assessment of preeclampsia and pregnancy-related hypertensive disorders.
Baert, Jonathan; McCarey, Catherine; Berkane, Nadia; Martinez de Tejada, Begoña; Vial, Yvan; Rieder, Wawrzyniec.
Affiliation
  • Baert J; Obstetric Unit, Woman-Mother-Child Department, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland / Faculty of Medicine, University of Lausanne, Switzerland.
  • McCarey C; Obstetric Division, Department of Paediatrics, Gynaecology and Obstetrics, University Hospitals of Geneva (HUG), Geneva, Switzerland / Faculty of Medicine, University of Geneva, Switzerland.
  • Berkane N; Obstetric Division, Department of Paediatrics, Gynaecology and Obstetrics, University Hospitals of Geneva (HUG), Geneva, Switzerland.
  • Martinez de Tejada B; Obstetric Division, Department of Paediatrics, Gynaecology and Obstetrics, University Hospitals of Geneva (HUG), Geneva, Switzerland / Faculty of Medicine, University of Geneva, Switzerland.
  • Vial Y; Obstetric Unit, Woman-Mother-Child Department, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland / Faculty of Medicine, University of Lausanne, Switzerland.
  • Rieder W; Obstetric Unit, Woman-Mother-Child Department, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland / Faculty of Medicine, University of Lausanne, Switzerland.
Swiss Med Wkly ; 151: w20533, 2021 07 05.
Article in En | MEDLINE | ID: mdl-34283894
ABSTRACT
Preeclampsia is a major cause of maternal and fetal morbidity and mortality. Early recognition of the disease may be challenging. Complications may precede the onset of clinical symptoms and medical intervention is often delayed. Moreover, in the absence of specific clinical signs, many patients will present symptoms mimicking the disease without ever being diagnosed with preeclampsia. This situation may, however, lead to medical interventions and cause unnecessary stress for the patient. For many years, research tried to evaluate the significance of serum biomarkers as early indicators of preeclampsia. Among many, the sFlt-1/PlGF ratio, given its performance, aroused the greatest interest. This article reviews current knowledge on the subject, focusing on a Swiss perspective.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pre-Eclampsia / Hypertension, Pregnancy-Induced Type of study: Diagnostic_studies Limits: Female / Humans / Pregnancy Language: En Journal: Swiss Med Wkly Journal subject: MEDICINA Year: 2021 Document type: Article Affiliation country: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pre-Eclampsia / Hypertension, Pregnancy-Induced Type of study: Diagnostic_studies Limits: Female / Humans / Pregnancy Language: En Journal: Swiss Med Wkly Journal subject: MEDICINA Year: 2021 Document type: Article Affiliation country: Switzerland