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Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics.
Beckert, Bertrand; Leroy, Elodie C; Sothiselvam, Shanmugapriya; Bock, Lars V; Svetlov, Maxim S; Graf, Michael; Arenz, Stefan; Abdelshahid, Maha; Seip, Britta; Grubmüller, Helmut; Mankin, Alexander S; Innis, C Axel; Vázquez-Laslop, Nora; Wilson, Daniel N.
Affiliation
  • Beckert B; Institute for Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany.
  • Leroy EC; Univ. Bordeaux, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, ARNA, UMR 5320, U1212, Institut Européen de Chimie et Biologie, Pessac, France.
  • Sothiselvam S; Center for Biomolecular Sciences, University of Illinois at Chicago, Chicago, IL, USA.
  • Bock LV; Theoretical and Computational Biophysics Department, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany. lbock@mpibpc.mpg.de.
  • Svetlov MS; Center for Biomolecular Sciences, University of Illinois at Chicago, Chicago, IL, USA.
  • Graf M; Institute for Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany.
  • Arenz S; Institute for Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany.
  • Abdelshahid M; Institute for Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany.
  • Seip B; Univ. Bordeaux, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, ARNA, UMR 5320, U1212, Institut Européen de Chimie et Biologie, Pessac, France.
  • Grubmüller H; Theoretical and Computational Biophysics Department, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
  • Mankin AS; Center for Biomolecular Sciences, University of Illinois at Chicago, Chicago, IL, USA.
  • Innis CA; Univ. Bordeaux, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, ARNA, UMR 5320, U1212, Institut Européen de Chimie et Biologie, Pessac, France. axel.innis@inserm.fr.
  • Vázquez-Laslop N; Center for Biomolecular Sciences, University of Illinois at Chicago, Chicago, IL, USA. nvazquez@uic.edu.
  • Wilson DN; Institute for Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany. daniel.wilson@chemie.uni-hamburg.de.
Nat Commun ; 12(1): 4466, 2021 07 22.
Article in En | MEDLINE | ID: mdl-34294725
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Synthesis Inhibitors / Macrolides / Ketolides / Anti-Bacterial Agents Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Germany Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Synthesis Inhibitors / Macrolides / Ketolides / Anti-Bacterial Agents Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Germany Country of publication: United kingdom