Little in vitro effect of remdesivir on mitochondrial respiration and monoamine oxidase activity in isolated mitochondria.

Fisar, Zdenek; Lupták, Matej; Hroudová, Jana

Fisar, Zdenek; Lupták, Matej; Hroudová, Jana.

Affiliation

Fisar Z; Charles University and General University Hospital in Prague, First Faculty of Medicine, Department of Psychiatry, Ke Karlovu 11, 121 28, Prague 2, Czech Republic. Electronic address: zfisar@lf1.cuni.cz.
Lupták M; Charles University and General University Hospital in Prague, First Faculty of Medicine, Institute of Pharmacology, Albertov 4, 128 00, Prague 2, Czech Republic.
Hroudová J; Charles University and General University Hospital in Prague, First Faculty of Medicine, Department of Psychiatry, Ke Karlovu 11, 121 28, Prague 2, Czech Republic.

Toxicol Lett ; 350: 143-151, 2021 Oct 10.

Article in En | MEDLINE | ID: mdl-34311047

Subject(s)

Antiviral Agents/pharmacology; Cell Respiration/drug effects; Cells, Cultured/drug effects; Mitochondria/drug effects; Mitochondria/metabolism; Monoamine Oxidase/drug effects; Monoamine Oxidase/metabolism; Animals; Humans; Models, Animal; Swine

Key words

Isolated mitochondria; Mitochondrial respiratory rate; Monoamine oxidase; Remdesivir; Respiratory complex

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Cells, Cultured / Cell Respiration / Mitochondria / Monoamine Oxidase Limits: Animals / Humans Language: En Journal: Toxicol Lett Year: 2021 Document type: Article Country of publication: Netherlands

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