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High-mass MALDI-MS unravels ligand-mediated G protein-coupling selectivity to GPCRs.
Wu, Na; Olechwier, Agnieszka M; Brunner, Cyrill; Edwards, Patricia C; Tsai, Ching-Ju; Tate, Christopher G; Schertler, Gebhard F X; Schneider, Gisbert; Deupi, Xavier; Zenobi, Renato; Ma, Pikyee.
Affiliation
  • Wu N; Department of Chemistry and Applied Biosciences, ETH Zürich, CH-8093 Zürich, Switzerland.
  • Olechwier AM; Laboratory of Biomolecular Research, Paul Scherrer Institute, CH-5232 Villigen PSI, Switzerland.
  • Brunner C; Department of Biology, ETH Zürich, CH-8093 Zürich, Switzerland.
  • Edwards PC; Department of Chemistry and Applied Biosciences, ETH Zürich, CH-8093 Zürich, Switzerland.
  • Tsai CJ; Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom.
  • Tate CG; Laboratory of Biomolecular Research, Paul Scherrer Institute, CH-5232 Villigen PSI, Switzerland.
  • Schertler GFX; Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom.
  • Schneider G; Laboratory of Biomolecular Research, Paul Scherrer Institute, CH-5232 Villigen PSI, Switzerland.
  • Deupi X; Department of Biology, ETH Zürich, CH-8093 Zürich, Switzerland.
  • Zenobi R; Department of Chemistry and Applied Biosciences, ETH Zürich, CH-8093 Zürich, Switzerland.
  • Ma P; Laboratory of Biomolecular Research, Paul Scherrer Institute, CH-5232 Villigen PSI, Switzerland.
Proc Natl Acad Sci U S A ; 118(31)2021 08 03.
Article in En | MEDLINE | ID: mdl-34326250
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Opioid / Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / GTP-Binding Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Document type: Article Affiliation country: Switzerland Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Opioid / Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / GTP-Binding Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Document type: Article Affiliation country: Switzerland Country of publication: United States