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Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload.
Vieira-Lara, Marcel A; Dommerholt, Marleen B; Zhang, Wenxuan; Blankestijn, Maaike; Wolters, Justina C; Abegaz, Fentaw; Gerding, Albert; van der Veen, Ydwine T; Thomas, Rachel; van Os, Ronald P; Reijngoud, Dirk-Jan; Jonker, Johan W; Kruit, Janine K; Bakker, Barbara M.
Affiliation
  • Vieira-Lara MA; Laboratory of Pediatrics, Systems Medicine of Metabolism and Signaling, University Medical Center Groningen, University of Groningen, Postbus 196, 9700, AD, Groningen, The Netherlands.
  • Dommerholt MB; Laboratory of Pediatrics, Systems Medicine of Metabolism and Signaling, University Medical Center Groningen, University of Groningen, Postbus 196, 9700, AD, Groningen, The Netherlands.
  • Zhang W; Laboratory of Pediatrics, Systems Medicine of Metabolism and Signaling, University Medical Center Groningen, University of Groningen, Postbus 196, 9700, AD, Groningen, The Netherlands.
  • Blankestijn M; Department of Analytical Biochemistry, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.
  • Wolters JC; Laboratory of Pediatrics, Systems Medicine of Metabolism and Signaling, University Medical Center Groningen, University of Groningen, Postbus 196, 9700, AD, Groningen, The Netherlands.
  • Abegaz F; Laboratory of Pediatrics, Systems Medicine of Metabolism and Signaling, University Medical Center Groningen, University of Groningen, Postbus 196, 9700, AD, Groningen, The Netherlands.
  • Gerding A; Department of Analytical Biochemistry, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.
  • van der Veen YT; Laboratory of Pediatrics, Systems Medicine of Metabolism and Signaling, University Medical Center Groningen, University of Groningen, Postbus 196, 9700, AD, Groningen, The Netherlands.
  • Thomas R; Laboratory of Pediatrics, Systems Medicine of Metabolism and Signaling, University Medical Center Groningen, University of Groningen, Postbus 196, 9700, AD, Groningen, The Netherlands.
  • van Os RP; Dutch Molecular Pathology Centre, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
  • Reijngoud DJ; Laboratory of Pediatrics, Systems Medicine of Metabolism and Signaling, University Medical Center Groningen, University of Groningen, Postbus 196, 9700, AD, Groningen, The Netherlands.
  • Jonker JW; Department of Analytical Biochemistry, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.
  • Kruit JK; Dutch Molecular Pathology Centre, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
  • Bakker BM; Central Animal Facility, Mouse Clinic for Cancer and Aging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
BMC Biol ; 19(1): 154, 2021 07 30.
Article in En | MEDLINE | ID: mdl-34330275
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance Type of study: Prognostic_studies Limits: Animals Language: En Journal: BMC Biol Journal subject: BIOLOGIA Year: 2021 Document type: Article Affiliation country: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance Type of study: Prognostic_studies Limits: Animals Language: En Journal: BMC Biol Journal subject: BIOLOGIA Year: 2021 Document type: Article Affiliation country: Netherlands