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Accuracy of a Self-Administered Online Cognitive Assessment in Detecting Amnestic Mild Cognitive Impairment.
Paterson, Theone S E; Sivajohan, Brintha; Gardner, Sandra; Binns, Malcolm A; Stokes, Kathryn A; Freedman, Morris; Levine, Brian; Troyer, Angela K.
Affiliation
  • Paterson TSE; Baycrest Health Sciences Centre, Toronto, Ontario, Canada.
  • Sivajohan B; Department of Psychology, University of Victoria, British Columbia, Canada.
  • Gardner S; Baycrest Health Sciences Centre, Toronto, Ontario, Canada.
  • Binns MA; Baycrest Health Sciences Centre, Toronto, Ontario, Canada.
  • Stokes KA; Dalla Lana School of Public Health, University of Toronto, Ontario, Canada.
  • Freedman M; Dalla Lana School of Public Health, University of Toronto, Ontario, Canada.
  • Levine B; Rotman Research Institute, Toronto, Ontario, Canada.
  • Troyer AK; Baycrest Health Sciences Centre, Toronto, Ontario, Canada.
J Gerontol B Psychol Sci Soc Sci ; 77(2): 341-350, 2022 02 03.
Article in En | MEDLINE | ID: mdl-34333629
OBJECTIVES: Our aim was to validate the online Brain Health Assessment (BHA) for detection of amnestic mild cognitive impairment (aMCI) compared to gold-standard neuropsychological assessment. We compared the diagnostic accuracy of the BHA to the Montreal Cognitive Assessment (MoCA). METHODS: Using a cross-sectional design, community-dwelling older adults completed a neuropsychological assessment, were diagnosed as normal cognition (NC) or aMCI, and completed the BHA and MoCA. Both logistic regression (LR) and penalized logistic regression (PLR) analyses determined BHA and demographic variables predicting aMCI; MoCA variables were similarly modeled. Diagnostic accuracy was compared using area under the receiver operating characteristic curve (ROC AUC) analyses. RESULTS: Ninety-one participants met inclusion criteria (51 aMCI, 40 NC). PLR modeling for the BHA indicated Face-Name Association, Spatial Working Memory, and age-predicted aMCI (ROC AUC = 0.76; 95% confidence interval [CI]: 0.66-0.86). Optimal cut-points resulted in 21% classified as aMCI (positive), 23% negative, and 56% inconclusive. For the MoCA, digits, abstraction, delayed recall, orientation, and age predicted aMCI (ROC AUC = 0.71; 95% CI: 0.61-0.82). Optimal cut-points resulted in 22% classified positive, 8% negative, and 70% inconclusive (LR results presented within). The BHA model classified fewer participants into the inconclusive category and more as negative for aMCI, compared to the MoCA model (Stuart-Maxwell p = .004). DISCUSSION: The self-administered BHA provides similar detection of aMCI as a clinician-administered screener (MoCA), with fewer participants classified inconclusively. The BHA has the potential to save practitioners time and decrease unnecessary referrals for a comprehensive assessment to determine the presence of aMCI.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diagnostic Self Evaluation / Cognitive Dysfunction / Internet-Based Intervention / Neuropsychological Tests Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Aged / Female / Humans / Male Language: En Journal: J Gerontol B Psychol Sci Soc Sci Journal subject: CIENCIAS SOCIAIS / GERIATRIA / PSICOLOGIA Year: 2022 Document type: Article Affiliation country: Canada Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diagnostic Self Evaluation / Cognitive Dysfunction / Internet-Based Intervention / Neuropsychological Tests Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Aged / Female / Humans / Male Language: En Journal: J Gerontol B Psychol Sci Soc Sci Journal subject: CIENCIAS SOCIAIS / GERIATRIA / PSICOLOGIA Year: 2022 Document type: Article Affiliation country: Canada Country of publication: United States