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Are Pt(IV) Prodrugs That Release Combretastatin A4 True Multi-action Prodrugs?
Schmidt, Claudia; Babu, Tomer; Kostrhunova, Hana; Timm, Annika; Basu, Uttara; Ott, Ingo; Gandin, Valentina; Brabec, Viktor; Gibson, Dan.
Affiliation
  • Schmidt C; Institute for Drug Research, School of Pharmacy, The Hebrew University, 91120 Jerusalem, Israel.
  • Babu T; Institute for Drug Research, School of Pharmacy, The Hebrew University, 91120 Jerusalem, Israel.
  • Kostrhunova H; Institute of Biophysics, Czech Academy of Sciences, Academy of Sciences, Kralovopolska 135, 61265 Brno, Czech Republic.
  • Timm A; Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Beethovenstrasse 55, 38106 Braunschweig, Germany.
  • Basu U; Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Beethovenstrasse 55, 38106 Braunschweig, Germany.
  • Ott I; Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Beethovenstrasse 55, 38106 Braunschweig, Germany.
  • Gandin V; Dipartimento di Scienze del Farmaco, Universita di Padova, Via Marzolo 5, 35131 Padova, Italy.
  • Brabec V; Institute of Biophysics, Czech Academy of Sciences, Academy of Sciences, Kralovopolska 135, 61265 Brno, Czech Republic.
  • Gibson D; Department of Biophysics, Faculty of Science, Palacky University in Olomouc, Slechtitelu 27, 78371 Olomouc, Czech Republic.
J Med Chem ; 64(15): 11364-11378, 2021 08 12.
Article in En | MEDLINE | ID: mdl-34342437
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organoplatinum Compounds / Prodrugs / Carbonic Anhydrase IV / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: Israel
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organoplatinum Compounds / Prodrugs / Carbonic Anhydrase IV / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: Israel