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On the evaluation of edgeless diode detectors for patient-specific QA in high-dose stereotactic radiosurgery.
De Martin, Elena; Alhujaili, Sultan; Fumagalli, Maria Luisa; Ghielmetti, Francesco; Marchetti, Marcello; Gallo, Pasqualina; Aquino, Domenico; Padelli, Francesco; Davis, Jeremy; Alnaghy, Saree; Carrara, Mauro; Fariselli, Laura; Rosenfeld, Anatoly B; Petasecca, Marco.
Affiliation
  • De Martin E; Fondazione IRCCS Istituto Neurologico Carlo Besta, Health Department, Via Giovanni Celoria 11, 20133 Milan, Italy. Electronic address: elena.demartin@istituto-besta.it.
  • Alhujaili S; Centre for Medical Radiation Physics, University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia; Medical Imaging Department, College of Applied Medical Sciences, Aljouf University, Aljouf 72388, Saudi Arabia. Electronic address: sfa744@uowmail.edu.au.
  • Fumagalli ML; Fondazione IRCCS Istituto Neurologico Carlo Besta, Health Department, Via Giovanni Celoria 11, 20133 Milan, Italy. Electronic address: marialuisa.fumagalli@istituto-besta.it.
  • Ghielmetti F; Fondazione IRCCS Istituto Neurologico Carlo Besta, Health Department, Via Giovanni Celoria 11, 20133 Milan, Italy. Electronic address: francesco.ghielmetti@istituto-besta.it.
  • Marchetti M; Fondazione IRCCS Istituto Neurologico Carlo Besta, Radiotherapy Unit, Department of Neurosurgery, Via Giovanni Celoria 11, 20133 Milan, Italy. Electronic address: marcello.marchetti@istituto-besta.it.
  • Gallo P; Fondazione IRCCS Istituto Neurologico Carlo Besta, Health Department, Via Giovanni Celoria 11, 20133 Milan, Italy. Electronic address: pasqualina.gallo@humanitas.it.
  • Aquino D; Fondazione IRCCS Istituto Neurologico Carlo Besta, Neuroradiology Unit, Via Giovanni Celoria 11, 20133 Milan, Italy. Electronic address: domenico.aquino@istituto-besta.it.
  • Padelli F; Fondazione IRCCS Istituto Neurologico Carlo Besta, Neuroradiology Unit, Via Giovanni Celoria 11, 20133 Milan, Italy. Electronic address: francesco.padelli@istituto-besta.it.
  • Davis J; Centre for Medical Radiation Physics, University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia. Electronic address: jeremyd@uow.edu.au.
  • Alnaghy S; Centre for Medical Radiation Physics, University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia. Electronic address: saree@uow.edu.au.
  • Carrara M; Fondazione IRCCS Istituto Nazionale Dei Tumori, s.s.d. di Fisica Medica, Dipartimento di Diagnostica per Immagini e Radioterapia, Via Giacomo Venezian 1, 20133 Milan, Italy. Electronic address: mauro.carrara@istitutotumori.mi.it.
  • Fariselli L; Fondazione IRCCS Istituto Neurologico Carlo Besta, Radiotherapy Unit, Department of Neurosurgery, Via Giovanni Celoria 11, 20133 Milan, Italy. Electronic address: laura.fariselli@istituto-besta.it.
  • Rosenfeld AB; Centre for Medical Radiation Physics, University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia. Electronic address: anatoly@uow.edu.au.
  • Petasecca M; Centre for Medical Radiation Physics, University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia.
Phys Med ; 89: 20-28, 2021 Sep.
Article in En | MEDLINE | ID: mdl-34343763
ABSTRACT

PURPOSE:

In this work, the potential of an innovative "edgeless" silicon diode was evaluated as a response to the still unmet need of a reliable tool for plan dosimetry verification of very high dose, non-coplanar, patient-specific radiosurgery treatments. In order to prove the effectiveness of the proposed technology, we focused on radiosurgical treatments for functional disease like tremor or pain.

METHODS:

The edgeless diodes response has been validated with respect to clinical practice standard detectors by reproducing the reference dosimetry data adopted for the Treatment Planning System. In order to evaluate the potential for radiosurgery patient-specific treatment plan verification, the anthropomorphic phantom Alderson RANDO has been adopted along with three edgeless sensors, one placed in the centre of the Planning Target Volume, one superiorly and one inferiorly.

RESULTS:

The reference dosimetry data obtained from the edgeless detectors are within 2.6% for output factor, off-axis ratio and well within 2% for tissue phantom ratio when compared to PTW 60,018 diode. The edgeless detectors measure a dose discrepancy of approximately 3.6% from the mean value calculated by the TPS. Larger discrepancies are obtained in very steep gradient dose regions when the sensors are placed outside the PTV.

CONCLUSIONS:

The angular independent edgeless diode is proposed as an innovative dosimeter for patient quality assurance of brain functional disorders and other radiosurgery treatments. The comparison of the diode measurements with TPS calculations confirms that edgeless diodes are suitable candidates for patient-specific dosimetric verification in very high dose ranges delivered by non-isocentric stereotactic radiosurgery modalities.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiosurgery Limits: Humans Language: En Journal: Phys Med Journal subject: BIOFISICA / BIOLOGIA / MEDICINA Year: 2021 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiosurgery Limits: Humans Language: En Journal: Phys Med Journal subject: BIOFISICA / BIOLOGIA / MEDICINA Year: 2021 Document type: Article
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