Advances in pulmonary drug delivery targeting microbial biofilms in respiratory diseases.
Nanomedicine (Lond)
; 16(21): 1905-1923, 2021 09.
Article
in En
| MEDLINE
| ID: mdl-34348474
ABSTRACT
The increasing burden of respiratory diseases caused by microbial infections poses an immense threat to global health. This review focuses on the various types of biofilms that affect the respiratory system and cause pulmonary infections, specifically bacterial biofilms. The article also sheds light on the current strategies employed for the treatment of such pulmonary infection-causing biofilms. The potential of nanocarriers as an effective treatment modality for pulmonary infections is discussed, along with the challenges faced during treatment and the measures that may be implemented to overcome these. Understanding the primary approaches of treatment against biofilm infection and applications of drug-delivery systems that employ nanoparticle-based approaches in the disruption of biofilms are of utmost interest which may guide scientists to explore the vistas of biofilm research while determining suitable treatment modalities for pulmonary respiratory infections.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pharmaceutical Preparations
/
Nanoparticles
Language:
En
Journal:
Nanomedicine (Lond)
Year:
2021
Document type:
Article
Affiliation country:
India