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Triterpenoids from the bark of Entandrophragma angolense.
Trinh, Binh T D; Bui, Dzung N; Nguyen, Ly T T; Nguyen, Hieu T; Nguyen, Chi N; Nguyen, Lien-Hoa D; Huynh, Tuyen N M; Cao, Tien T C; Nguyen, Le-Thu T.
Affiliation
  • Trinh BTD; Natural Product and Medicinal Chemistry Lab, Faculty of Chemistry, VNUHCM-University of Science (HCMUS), Ho Chi Minh City, Vietnam.
  • Bui DN; Department of Analytical Chemistry, HCMUS, Ho Chi Minh City, Vietnam.
  • Nguyen LTT; Natural Product and Medicinal Chemistry Lab, Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Vietnam.
  • Nguyen HT; Natural Product and Medicinal Chemistry Lab, Faculty of Chemistry, VNUHCM-University of Science (HCMUS), Ho Chi Minh City, Vietnam.
  • Nguyen CN; Natural Product and Medicinal Chemistry Lab, Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Vietnam.
  • Nguyen LD; Natural Product and Medicinal Chemistry Lab, Faculty of Chemistry, VNUHCM-University of Science (HCMUS), Ho Chi Minh City, Vietnam.
  • Huynh TNM; Natural Product and Medicinal Chemistry Lab, Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Vietnam.
  • Cao TTC; Natural Product and Medicinal Chemistry Lab, Vietnam National University Ho Chi Minh City, Ho Chi Minh City, Vietnam.
  • Nguyen LT; Department of Organic Chemistry, HCMUS, Ho Chi Minh City, Vietnam.
Nat Prod Res ; 37(2): 240-247, 2023 Jan.
Article in En | MEDLINE | ID: mdl-34351811
ABSTRACT
Two new triterpenoids, entanolide (1) and methyl 3,4-secotirucalla-23-oxo-4(28),7,24-trien-21-al-3-oate (2), together with nine known compounds (3-11), were isolated from the bark of Entandrophragma angolense. Their structures were elucidated based on spectroscopic analyses, mainly 1 D and 2 D NMR spectral data. Compounds 1-6 and 8 were evaluated for their cytotoxicity against HepG2 cells, and compounds 2-5 exhibited weak activities.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triterpenes / Meliaceae Limits: Humans Language: En Journal: Nat Prod Res Year: 2023 Document type: Article Affiliation country: Vietnam
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triterpenes / Meliaceae Limits: Humans Language: En Journal: Nat Prod Res Year: 2023 Document type: Article Affiliation country: Vietnam