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Preclinical and phase I studies of KA2237, a selective and potent inhibitor of PI3K ß/δ in relapsed refractory B cell lymphoma.
Nastoupil, Loretta J; Neelapu, Sattva S; Davis, Richard Eric; Samaniego, Felipe; Fowler, Nathan H; Westin, Jason; Lee, Hun Ju; Wang, Michael; Hagemeister, Fredrick; Cecil, Alexander R L; Dow, James; Haque, Kemal; Silva, Franck A; Whale, Andrew; Lensun, Letitia; Bone, Elisabeth A; McElwaine-Johnn, Hilary; Beer, Philip A.
Affiliation
  • Nastoupil LJ; Department of Lymphoma/Myeloma, UT MD Anderson Cancer Center, Houston, TX, USA.
  • Neelapu SS; Department of Lymphoma/Myeloma, UT MD Anderson Cancer Center, Houston, TX, USA.
  • Davis RE; Department of Lymphoma/Myeloma, UT MD Anderson Cancer Center, Houston, TX, USA.
  • Samaniego F; Department of Lymphoma/Myeloma, UT MD Anderson Cancer Center, Houston, TX, USA.
  • Fowler NH; Department of Lymphoma/Myeloma, UT MD Anderson Cancer Center, Houston, TX, USA.
  • Westin J; Department of Lymphoma/Myeloma, UT MD Anderson Cancer Center, Houston, TX, USA.
  • Lee HJ; Department of Lymphoma/Myeloma, UT MD Anderson Cancer Center, Houston, TX, USA.
  • Wang M; Department of Lymphoma/Myeloma, UT MD Anderson Cancer Center, Houston, TX, USA.
  • Hagemeister F; Department of Lymphoma/Myeloma, UT MD Anderson Cancer Center, Houston, TX, USA.
  • Cecil ARL; Karus Therapeutics Ltd., Harwell, UK.
  • Dow J; Karus Therapeutics Ltd., Harwell, UK.
  • Haque K; Karus Therapeutics Ltd., Harwell, UK.
  • Silva FA; Karus Therapeutics Ltd., Harwell, UK.
  • Whale A; Karus Therapeutics Ltd., Harwell, UK.
  • Lensun L; Karus Therapeutics Ltd., Harwell, UK.
  • Bone EA; Karus Therapeutics Ltd., Harwell, UK.
  • McElwaine-Johnn H; Karus Therapeutics Ltd., Harwell, UK.
  • Beer PA; Karus Therapeutics Ltd., Harwell, UK.
Leuk Lymphoma ; 62(14): 3452-3462, 2021 12.
Article in En | MEDLINE | ID: mdl-34365878

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, Non-Hodgkin / Lymphoma, B-Cell / Lymphoma, Follicular Limits: Aged / Humans Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, Non-Hodgkin / Lymphoma, B-Cell / Lymphoma, Follicular Limits: Aged / Humans Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States