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Mutations in CRBN and other cereblon pathway genes are infrequently associated with acquired resistance to immunomodulatory drugs.
Jones, J R; Barber, A; Le Bihan, Y-V; Weinhold, N; Ashby, C; Walker, B A; Wardell, C P; Wang, H; Kaiser, M F; Jackson, G H; Davies, F E; Chopra, R; Morgan, G J; Pawlyn, C.
Affiliation
  • Jones JR; The Institute of Cancer Research, London, UK. Johnjones7@nhs.net.
  • Barber A; Brighton and Sussex Medical School, Brighton, UK. Johnjones7@nhs.net.
  • Le Bihan YV; Kings College Hospital NHS Foundation Trust, London, UK. Johnjones7@nhs.net.
  • Weinhold N; The Institute of Cancer Research, London, UK.
  • Ashby C; The Institute of Cancer Research, London, UK.
  • Walker BA; Department of Internal Medicine V, University Hospital of Heidelberg, Heidelberg, Germany.
  • Wardell CP; Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Arkansas, USA.
  • Wang H; Indiana University School of Medicine, Indiana, USA.
  • Kaiser MF; Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Arkansas, USA.
  • Jackson GH; The Institute of Cancer Research, London, UK.
  • Davies FE; The Institute of Cancer Research, London, UK.
  • Chopra R; The Royal Marsden Hospital, London, UK.
  • Morgan GJ; Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Pawlyn C; Perlmutter Cancer Center, NYU Langone Health, New York, USA.
Leukemia ; 35(10): 3017-3020, 2021 10.
Article in En | MEDLINE | ID: mdl-34373585
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers, Tumor / Drug Resistance, Neoplasm / Ubiquitin-Protein Ligases / Adaptor Proteins, Signal Transducing / Immunomodulating Agents / Multiple Myeloma / Mutation Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2021 Document type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers, Tumor / Drug Resistance, Neoplasm / Ubiquitin-Protein Ligases / Adaptor Proteins, Signal Transducing / Immunomodulating Agents / Multiple Myeloma / Mutation Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2021 Document type: Article Affiliation country: United kingdom