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Design, synthesis and anticancer evaluation of new 4-anilinoquinoline-3-carbonitrile derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers.
Zou, Min; Li, Jiawen; Jin, Bo; Wang, Mingsheng; Chen, Huiping; Zhang, Zhuangli; Zhang, Changzheng; Zhao, Zhihong; Zheng, Liyun.
Affiliation
  • Zou M; Henan Key Laboratory for Pharmacology of Liver Diseases, Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
  • Li J; Henan Key Laboratory for Pharmacology of Liver Diseases, Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
  • Jin B; Department of Ophthalmology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
  • Wang M; Henan Key Laboratory for Pharmacology of Liver Diseases, Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
  • Chen H; Henan Key Laboratory for Pharmacology of Liver Diseases, Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
  • Zhang Z; Henan Key Laboratory for Pharmacology of Liver Diseases, Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
  • Zhang C; Henan Key Laboratory for Pharmacology of Liver Diseases, Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
  • Zhao Z; Henan Key Laboratory for Pharmacology of Liver Diseases, Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
  • Zheng L; Henan Key Laboratory for Pharmacology of Liver Diseases, Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China. Electronic address: 360489418@qq.com.
Bioorg Chem ; 114: 105200, 2021 09.
Article in En | MEDLINE | ID: mdl-34375195
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Drug Design / Apoptosis / Receptor, ErbB-2 / Protein Kinase Inhibitors / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Bioorg Chem Year: 2021 Document type: Article Affiliation country: China Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Drug Design / Apoptosis / Receptor, ErbB-2 / Protein Kinase Inhibitors / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Bioorg Chem Year: 2021 Document type: Article Affiliation country: China Country of publication: United States