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SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export: genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis.
Castelli, Lydia M; Cutillo, Luisa; Souza, Cleide Dos Santos; Sanchez-Martinez, Alvaro; Granata, Ilaria; Lin, Ya-Hui; Myszczynska, Monika A; Heath, Paul R; Livesey, Matthew R; Ning, Ke; Azzouz, Mimoun; Shaw, Pamela J; Guarracino, Mario R; Whitworth, Alexander J; Ferraiuolo, Laura; Milo, Marta; Hautbergue, Guillaume M.
Affiliation
  • Castelli LM; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385 Glossop Road, Sheffield, S10 2HQ, UK.
  • Cutillo L; School of Mathematics, University of Leeds, Leeds, LS2 9JT, UK.
  • Souza CDS; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385 Glossop Road, Sheffield, S10 2HQ, UK.
  • Sanchez-Martinez A; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.
  • Granata I; National Research Council of Italy, High Performance Computing and Networking Institute (ICAR-CNR), 111 Via Pietro Castellino, 80131, Naples, Italy.
  • Lin YH; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385 Glossop Road, Sheffield, S10 2HQ, UK.
  • Myszczynska MA; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385 Glossop Road, Sheffield, S10 2HQ, UK.
  • Heath PR; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385 Glossop Road, Sheffield, S10 2HQ, UK.
  • Livesey MR; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385 Glossop Road, Sheffield, S10 2HQ, UK.
  • Ning K; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • Azzouz M; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385 Glossop Road, Sheffield, S10 2HQ, UK.
  • Shaw PJ; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • Guarracino MR; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385 Glossop Road, Sheffield, S10 2HQ, UK.
  • Whitworth AJ; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • Ferraiuolo L; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385 Glossop Road, Sheffield, S10 2HQ, UK.
  • Milo M; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.
  • Hautbergue GM; National Research Council of Italy, High Performance Computing and Networking Institute (ICAR-CNR), 111 Via Pietro Castellino, 80131, Naples, Italy.
Mol Neurodegener ; 16(1): 53, 2021 08 10.
Article in En | MEDLINE | ID: mdl-34376242
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA / Active Transport, Cell Nucleus / Serine-Arginine Splicing Factors / C9orf72 Protein / Amyotrophic Lateral Sclerosis / Neurons Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Neurodegener Year: 2021 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA / Active Transport, Cell Nucleus / Serine-Arginine Splicing Factors / C9orf72 Protein / Amyotrophic Lateral Sclerosis / Neurons Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Neurodegener Year: 2021 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom