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Development of mammary cancer in γ-irradiated F1 hybrids of susceptible Sprague-Dawley and resistant Copenhagen rats, with copy-number losses that pinpoint potential tumor suppressors.
Nishimura, Mayumi; Daino, Kazuhiro; Fukuda, Maki; Tanaka, Ikuya; Moriyama, Hitomi; Showler, Kaye; Nishimura, Yukiko; Takabatake, Masaru; Kokubo, Toshiaki; Ishikawa, Atsuko; Inoue, Kazumasa; Fukushi, Masahiro; Kakinuma, Shizuko; Imaoka, Tatsuhiko; Shimada, Yoshiya.
Affiliation
  • Nishimura M; Department of Radiation Effects Research, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
  • Daino K; Department of Radiation Effects Research, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
  • Fukuda M; Department of Radiological Sciences, Tokyo Metropolitan University, Tokyo, Japan.
  • Tanaka I; Radiobiology for Children's Health Research Group, Research Center for Radiation Protection, National Institute of Radiological Sciences, Chiba, Japan.
  • Moriyama H; Department of Radiological Sciences, Tokyo Metropolitan University, Tokyo, Japan.
  • Showler K; Radiobiology for Children's Health Research Group, Research Center for Radiation Protection, National Institute of Radiological Sciences, Chiba, Japan.
  • Nishimura Y; Department of Radiation Effects Research, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
  • Takabatake M; Department of Radiological Sciences, Tokyo Metropolitan University, Tokyo, Japan.
  • Kokubo T; Department of Radiological Sciences, Tokyo Metropolitan University, Tokyo, Japan.
  • Ishikawa A; Radiobiology for Children's Health Research Group, Research Center for Radiation Protection, National Institute of Radiological Sciences, Chiba, Japan.
  • Inoue K; Department of Radiation Effects Research, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
  • Fukushi M; Department of Radiation Effects Research, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
  • Kakinuma S; Department of Radiological Sciences, Tokyo Metropolitan University, Tokyo, Japan.
  • Imaoka T; Laboratory Animal and Genome Sciences Section, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
  • Shimada Y; Department of Radiation Effects Research, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
PLoS One ; 16(8): e0255968, 2021.
Article in En | MEDLINE | ID: mdl-34388197
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Genes, Tumor Suppressor / Chromosome Aberrations / Genetic Predisposition to Disease / DNA Copy Number Variations / Gamma Rays / Mammary Neoplasms, Experimental Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2021 Document type: Article Affiliation country: Japan
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Genes, Tumor Suppressor / Chromosome Aberrations / Genetic Predisposition to Disease / DNA Copy Number Variations / Gamma Rays / Mammary Neoplasms, Experimental Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2021 Document type: Article Affiliation country: Japan