A red-emissive two-photon fluorescent probe for mitochondrial sodium ions in live tissue.
Chem Commun (Camb)
; 57(71): 8929-8932, 2021 Sep 06.
Article
in En
| MEDLINE
| ID: mdl-34397047
ABSTRACT
A cyclocyanine (CC)-based organic small molecule two-photon (TP) fluorescent probe (CCNa1) was developed for mitochondrial sodium ion sensing. CCNa1 exhibits a low solvatochromic shift and strong TP fluorescence enhancement at 575 nm upon binding to Na+ and is insensitive to other metal ions and to pH. CCNa1 demonstrated fast cell loading ability, biocompatibility, and sensitive response to mitochondrial Na+ influx in live cells and mouse brain tissue.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sodium
/
Fluorescent Dyes
/
Mitochondria
Limits:
Animals
/
Humans
Language:
En
Journal:
Chem Commun (Camb)
Journal subject:
QUIMICA
Year:
2021
Document type:
Article
Affiliation country:
South Korea