Successful management of small cell neuroendocrine carcinoma of the ureter with neoadjuvant chemotherapy and adjuvant chemoradiation: case report and literature review.
BMJ Case Rep
; 14(8)2021 Aug 17.
Article
in En
| MEDLINE
| ID: mdl-34404642
ABSTRACT
Neuroendocrine tumours (NETs) of the urinary tract are rare, and the urinary bladder is the the most common primary site. Primary ureteric NET is rarer with under 80 cases reported in the literature thus far. Most of these tumours are of the high-grade small cell neuroendocrine carcinoma subtype, which has a worse prognosis. Neoadjuvant chemotherapy has a proven role in the management of NET of the bladder as it downstages the tumour, which may add to significant recurrence-free survival and overall survival. We report the successful management of a patient with locally advanced small cell neuroendocrine carcinoma of the ureter, who had a pathological complete response after neoadjuvant chemotherapy with etoposide and cisplatin. He subsequently received adjuvant chemotherapy followed by radiation and is recurrence-free at a follow-up of 1 year.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ureter
/
Carcinoma, Neuroendocrine
Type of study:
Prognostic_studies
Limits:
Humans
/
Male
Language:
En
Journal:
BMJ Case Rep
Year:
2021
Document type:
Article
Affiliation country:
India