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Development of the alopecia areata scale for clinical use: Results of an academic-industry collaborative effort.
King, Brett A; Mesinkovska, Natasha Atanaskova; Craiglow, Brittany; Kindred, Chesahna; Ko, Justin; McMichael, Amy; Shapiro, Jerry; Goh, Carolyn; Mirmirani, Paradi; Tosti, Antonella; Hordinsky, Maria; Huang, Kathie P; Castelo-Soccio, Leslie; Bergfeld, Wilma; Paller, Amy S; Mackay-Wiggan, Julian; Glashofer, Marc; Aguh, Crystal; Piliang, Melissa; Yazdan, Pedram; Lo Sicco, Kristen; Cassella, James V; Koenigsberg, Justine; Ahluwalia, Gurpreet; Ghorayeb, Eric; Fakharzadeh, Steven; Napatalung, Lynne; Gandhi, Kavita; DeLozier, Amy M; Nunes, Fabio P; Senna, Maryanne M.
Affiliation
  • King BA; Department of Dermatology, Yale University, New Haven, Connecticut. Electronic address: brett.king@yale.edu.
  • Mesinkovska NA; Department of Dermatology, University of California, Irvine, California.
  • Craiglow B; Department of Dermatology, Yale University, New Haven, Connecticut.
  • Kindred C; Howard University, Washington, District of Columbia.
  • Ko J; Stanford University, Stanford, California.
  • McMichael A; Wake Forest Baptist Health, Winston-Salem, North Carolina.
  • Shapiro J; New York University, Langone Health, New York, New York.
  • Goh C; University of California, Los Angeles, California.
  • Mirmirani P; Kaiser Permanente Vallejo Medical Center, Vallejo, California.
  • Tosti A; University of Miami, Miami, Florida.
  • Hordinsky M; University of Minnesota, Minneapolis, Minnesota.
  • Huang KP; Brigham and Women's Hospital, Boston, Massachusetts.
  • Castelo-Soccio L; Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Bergfeld W; Cleveland Clinic, Cleveland, Ohio.
  • Paller AS; Northwestern University, Evanston, Illinois.
  • Mackay-Wiggan J; Columbia University, New York, New York.
  • Glashofer M; The Dermatology Group, West Orange, New Jersey.
  • Aguh C; Johns Hopkins University, Baltimore, Maryland.
  • Piliang M; Cleveland Clinic, Cleveland, Ohio.
  • Yazdan P; Northwestern University, Evanston, Illinois.
  • Lo Sicco K; New York University, Langone Health, New York, New York.
  • Cassella JV; Concert Pharmaceuticals Inc, Lexington, Massachusetts.
  • Koenigsberg J; Concert Pharmaceuticals Inc, Lexington, Massachusetts.
  • Ahluwalia G; Arena Pharmaceuticals Inc, San Diego, California.
  • Ghorayeb E; Janssen Global Services, LLC, Horsham, Pennsylvania.
  • Fakharzadeh S; Janssen Global Services, LLC, Horsham, Pennsylvania.
  • Napatalung L; Pfizer, New York, New York.
  • Gandhi K; Pfizer, New York, New York.
  • DeLozier AM; Eli Lilly and Company, Indianapolis, Indiana.
  • Nunes FP; Janssen Global Services, LLC, Horsham, Pennsylvania; Eli Lilly and Company, Indianapolis, Indiana.
  • Senna MM; Dermatology Associates, Massachusetts General Hospital, Boston, Massachusetts. Electronic address: msenna@partners.org.
J Am Acad Dermatol ; 86(2): 359-364, 2022 02.
Article in En | MEDLINE | ID: mdl-34474079
BACKGROUND: The current classification for alopecia areata (AA) does not provide a consistent assessment of disease severity. OBJECTIVE: To develop an AA severity scale based on expert experience. METHODS: A modified Delphi process was utilized. An advisory group of 22 AA clinical experts from the United States was formed to develop this AA scale. Representatives from the pharmaceutical industry provided feedback during its development. RESULTS: Survey responses were used to draft severity criteria, aspiring to develop a simple scale that may be easily applied in clinical practice. A consensus vote was held to determine the final AA severity statement, with all AA experts agreeing to adopt the proposed scale. LIMITATIONS: The scale is a static assessment intended to be used in clinical practice and not clinical trials. CONCLUSION: The final AA disease severity scale, anchored in the extent of hair loss, captures key features commonly used by AA experts in clinical practice. This scale will better aid clinicians in appropriately assessing severity in patients with this common disease.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alopecia Areata Type of study: Diagnostic_studies / Guideline Limits: Humans Language: En Journal: J Am Acad Dermatol Year: 2022 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alopecia Areata Type of study: Diagnostic_studies / Guideline Limits: Humans Language: En Journal: J Am Acad Dermatol Year: 2022 Document type: Article Country of publication: United States