Role of subcutaneous implantable loop recorder for the diagnosis of arrhythmias in Brugada syndrome: A United Kingdom single-center experience.
Heart Rhythm
; 19(1): 70-78, 2022 01.
Article
in En
| MEDLINE
| ID: mdl-34487893
ABSTRACT
BACKGROUND:
Experience with implantable loop recorders (ILRs) in Brugada syndrome (BrS) is limited.OBJECTIVE:
The purpose of this study was to evaluate the indications and yield of ILR monitoring in a single-center BrS registry.METHODS:
Demographic, clinical and follow-up data of BrS patients with ILR were collected.RESULTS:
Of 415 BrS patients recruited consecutively, 50 (12%) received an ILR (58% male). Mean age at ILR implantation was 44 ± 15 years. Thirty-one (62%) had experienced syncopal or presyncopal episodes, and 23 (46%) had palpitations. During median follow-up of 28 months (range 1-68), actionable events were detected in 11 subjects (22%); 7 had recurrences of syncope/presyncope, with 4 showing defects in sinus node function or atrioventricular conduction. New supraventricular tachyarrhythmias were recorded in 6 subjects; a run of fast nonsustained ventricular tachycardia was detected in 1 patient. Patients implanted with an ILR were less likely to show a spontaneous type 1 pattern or depolarization electrocardiographic (ECG) abnormalities compared to those receiving a primary prevention implantable-cardioverter defibrillator. Age at implantation, gender, Shanghai score, and ECG parameters did not differ between subjects with and those without actionable events. ILR-related complications occurred in 3 cases (6%).CONCLUSION:
In a large cohort of BrS patients, continuous ILR monitoring yielded a diagnosis of tachy- or bradyarrhythmic episodes in 22% of cases. Recurrences of syncope were associated with bradyarrhythmic events. Use of ILR can be helpful in guiding the management of low-/intermediate-risk BrS patients and ascertaining the cause of unexplained syncope.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Syncope
/
Electrocardiography, Ambulatory
/
Brugada Syndrome
Type of study:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Heart Rhythm
Year:
2022
Document type:
Article
Affiliation country:
United kingdom